Evidence map›Paper›PMID 30587792›Full record

ArticleInternational journal of molecular sciences2018

The Unique Mechanisms of Cellular Proliferation, Migration and Apoptosis are Regulated through Oocyte Maturational Development-A Complete Transcriptomic and Histochemical Study.

Błażej Chermuła, Maciej Brązert, Michal Jeseta, Katarzyna Ożegowska, Patrycja Sujka-Kordowska, Aneta Konwerska, Artur Bryja, Wiesława Kranc, Maurycy Jankowski, Mariusz J Nawrocki and 13 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 4 institutions in 2 countries.

Błażej ChermułaDivision of Infertility and Reproductive Endocrinology, Department of Gynecology, Obstetrics and Gynecological Oncology, Poznan University of Medical Sciences, 60-535 Poznań, Poland. blazej.chermula@wp.pl.
Maciej BrązertDivision of Infertility and Reproductive Endocrinology, Department of Gynecology, Obstetrics and Gynecological Oncology, Poznan University of Medical Sciences, 60-535 Poznań, Poland. maciejbrazert@ump.edu.pl.
Michal JesetaDepartment of Obstetrics and Gynecology, University Hospital and Masaryk University, 601 77 Brno, Czech Republic. jeseta@gmail.com.
Katarzyna OżegowskaDivision of Infertility and Reproductive Endocrinology, Department of Gynecology, Obstetrics and Gynecological Oncology, Poznan University of Medical Sciences, 60-535 Poznań, Poland. katarzyna.ozegowska@ump.edu.pl.
Patrycja Sujka-KordowskaDepartment of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznań, Poland. psujka@ump.edu.pl.
Aneta KonwerskaDepartment of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznań, Poland. akonwer@ump.edu.pl.
Artur BryjaDepartment of Anatomy, Poznan University of Medical Sciences, 60-781 Poznań, Poland. abryja@ump.edu.pl.
Wiesława KrancDepartment of Anatomy, Poznan University of Medical Sciences, 60-781 Poznań, Poland. wkranc@ump.edu.pl.
Maurycy JankowskiDepartment of Anatomy, Poznan University of Medical Sciences, 60-781 Poznań, Poland. m.jankowski.14@aberdeen.ac.uk.ORCID 0000-0001-9476-0235
Mariusz J NawrockiDepartment of Anatomy, Poznan University of Medical Sciences, 60-781 Poznań, Poland. mjnawrocki@ump.edu.pl.ORCID 0000-0003-3753-755X
Ievgeniia KocherovaDepartment of Anatomy, Poznan University of Medical Sciences, 60-781 Poznań, Poland. ikocherova@ump.edu.pl.
Piotr CelichowskiDepartment of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznań, Poland. pcelichowski@ump.edu.pl.
Blanka BorowiecDepartment of Anatomy, Poznan University of Medical Sciences, 60-781 Poznań, Poland. blanka.maria.b@gmail.com.
Małgorzata PopisDepartment of Anatomy, Poznan University of Medical Sciences, 60-781 Poznań, Poland. malgorzatapopis111@gmail.com.
Joanna Budna-TukanDepartment of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznań, Poland. jbudna@ump.edu.pl.
Paweł AntosikVeterinary Center, Nicolaus Copernicus University in Torun, 87-100 Toruń, Poland. pantosik@umk.pl.
Dorota BukowskaVeterinary Center, Nicolaus Copernicus University in Torun, 87-100 Toruń, Poland. dbukowska@umk.pl.
Klaus P BrussowVeterinary Center, Nicolaus Copernicus University in Torun, 87-100 Toruń, Poland. prof.bruessow@gmail.com.
Leszek PawelczykDivision of Infertility and Reproductive Endocrinology, Department of Gynecology, Obstetrics and Gynecological Oncology, Poznan University of Medical Sciences, 60-535 Poznań, Poland. pawelczyk.leszek@ump.edu.pl.
Małgorzata BruskaDepartment of Anatomy, Poznan University of Medical Sciences, 60-781 Poznań, Poland. mbruska@ump.edu.pl.
Maciej ZabelDepartment of Histology and Embryology, Wroclaw University of Medical Sciences, 50-368 Wrocław, Poland. mazab@ump.edu.pl.
Michał NowickiDepartment of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznań, Poland. mnowicki@ump.edu.pl.
Bartosz KempistyDepartment of Obstetrics and Gynecology, University Hospital and Masaryk University, 601 77 Brno, Czech Republic. bkempisty@ump.edu.pl.
Poznan University of Medical Sciences · PLNicolaus Copernicus University · PLMasaryk University · CZWroclaw Medical University · PL

Funding

Narodowe Centrum Nauki UMO-2016/21/B/NZ9/03535
6 · The paper itself

Abstract

The growth and development of oocyte affect the functional activities of the surrounding somatic cells. These cells are regulated by various types of hormones, proteins, metabolites, and regulatory molecules through gap communication, ultimately leading to the development and maturation of oocytes. The close association between somatic cells and oocytes, which together form the cumulus-oocyte complexes (COCs), and their bi-directional communication are crucial for the acquisition of developmental competences by the oocyte. In this study, oocytes were extracted from the ovaries obtained from crossbred landrace gilts and subjected to in vitro maturation. RNA isolated from those oocytes was used for the subsequent microarray analysis. The data obtained shows, for the first time, variable levels of gene expression (fold changes higher than |2| and adjusted

Indexed as

TranscriptomeAnimalsApoptosisCell MovementCell ProliferationCumulus CellsDown-RegulationFemaleGene Expression ProfilingGene Regulatory NetworksIn Vitro Oocyte Maturation TechniquesOligonucleotide Array Sequence AnalysisOocytesRNASwineUp-RegulationRNAcellular competencemicroarrayoocytespig

Identifiers

PMID30587792
PMCPMC6337548
OpenAlexW2906410628

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.