Evidence map›Paper›PMID 30587769›Full record

ReviewBiosensors2018

Multiplex Lateral Flow Immunoassay: An Overview of Strategies towards High-throughput Point-of-Need Testing.

Laura Anfossi, Fabio Di Nardo, Simone Cavalera, Cristina Giovannoli, Claudio Baggiani

Abstract readReview
In one paragraph

Review in Biosensors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 1 synthesis or guideline pooled it.

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22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Laura AnfossiDepartment of Chemistry, University of Turin, Via Giuria, 5, I-10125 Turin, Italy. laura.anfossi@unito.it.ORCID 0000-0002-2920-0140
Fabio Di NardoDepartment of Chemistry, University of Turin, Via Giuria, 5, I-10125 Turin, Italy. fabio.dinardo@unito.it.ORCID 0000-0003-0497-4251
Simone CavaleraDepartment of Chemistry, University of Turin, Via Giuria, 5, I-10125 Turin, Italy. simone.cavalera@unito.it.
Cristina GiovannoliDepartment of Chemistry, University of Turin, Via Giuria, 5, I-10125 Turin, Italy. cristina.giovannoli@unito.it.
Claudio BaggianiDepartment of Chemistry, University of Turin, Via Giuria, 5, I-10125 Turin, Italy. claudio.baggiani@unito.it.ORCID 0000-0003-1024-2532

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Simultaneous measurement of different substances from a single sample is an emerging issue for achieving efficient and high-throughput detection in several fields of application. Although immunoanalytical techniques have well-established and prevailing advantages over alternative screening analytical platforms, one of the incoming challenges for immunoassay is exact multiplexing. Lateral flow immunoassay (LFIA) is a leading immunoanalytical technique for onsite analysis, thanks to its simplicity, rapidity, and cost-effectiveness. Moreover, LFIA architecture is adaptable to multiplexing, and is therefore a possible answer to the pressing demand of multiplexing point-of-need analysis. This review presents an overview of diverse approaches for multiplex LFIA, with a special focus on strategies based on new types of magnetic, fluorescent, and colored labels.

Indexed as

Biosensing TechniquesHigh-Throughput Screening AssaysImmunoassayimmunoassayimmunochromatographic testpoint-of-care testingrapid test

Identifiers

PMID30587769
PMCPMC6468474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.