Evidence map›Paper›PMID 30587626›Full record

ArticleIn vivo (Athens, Greece)

Prognostic Value of Red Blood Cell Distribution Width in Non-small Cell Lung Cancer Treated With Anti-programmed Cell Death-1 Antibody.

Tatsunori Kiriu, Masatsugu Yamamoto, Tatsuya Nagano, Kiyoko Koyama, Masahiro Katsurada, Daisuke Tamura, Kyosuke Nakata, Motoko Tachihara, Kazuyuki Kobayashi, Yoshihiro Nishimura

Abstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Uncovering prognostic biomarkers through a pharmacovigilance study: the case of RDW.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
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  11. The association between RDW and survival of patients with squamous cell carcinoma of the tongue. Simple, cheap and convenient?Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tatsunori KiriuDivision of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Masatsugu YamamotoDivision of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan myamamot@med.kobe-u.ac.jp.
Tatsuya NaganoDivision of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Kiyoko KoyamaDivision of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Masahiro KatsuradaDivision of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Daisuke TamuraDivision of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Kyosuke NakataDivision of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Motoko TachiharaDivision of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Kazuyuki KobayashiDivision of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Yoshihiro NishimuraDivision of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimRed cell distribution width (RDW) has been reported to reflect the inflammation and nutrition status and predict prognosis of non-small cell lung cancer (NSCLC) patients treated with anti-programmed cell death-1 (PD-1) antibody. The aim of this study was to analyze the correlation between RDW and prognosis of NSCLC patients. PATIENTS AND

methodsWe collected retrospective data on consecutive NSCLC patients treated with anti-PD-1 antibody from December 2015 to April 2018 at the Kobe University Hospital, Japan.

resultsForty-seven patients were treated. Patients with RDW ≥16% had a significantly shorter OS (p=0.010) compared to those with RDW <16%. In multivariate analysis, RDW ≥16% was an independent factor predicting poor prognosis (p=0.019).

conclusionPre-treatment RDW ≥16% is an indicator of poor prognosis. RDW is an inexpensive, convenient, and routinely available marker of prognosis.

Indexed as

ErythrocytesAdultAgedAged, 80 and overAntibodies, Anti-IdiotypicCarcinoma, Non-Small-Cell LungDisease-Free SurvivalFemaleHumansMaleMiddle AgedPrognosisProgrammed Cell Death 1 ReceptorRetrospective StudiesAntibodies, Anti-IdiotypicPDCD1 protein, humanProgrammed Cell Death 1 Receptoranti-programmed cell death-1 antibodyneutrophil-to-lymphocyte rationon-small cell lung cancerprognostic markerRed blood cell distribution width

Identifiers

PMID30587626
PMCPMC6364053

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.