Evidence map›Paper›PMID 30587601›Full record

ArticleIn vivo (Athens, Greece)

Immunohistochemical Evidence of the Involvement of Natural Killer (CD161

Jana Kovalska, Monika Cervinkova, Eva Chmelikova, Daniela Planska, Jana Cizkova, Vratislav Horak

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jana KovalskaInstitute of Animal Physiology and Genetics, the Czech Academy of Sciences, Libechov, Czech Republic jana.bohacova@fnkv.cz.
Monika CervinkovaInstitute of Animal Physiology and Genetics, the Czech Academy of Sciences, Libechov, Czech Republic.
Eva ChmelikovaDepartment of Veterinary Sciences, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences, Prague, Czech Republic.
Daniela PlanskaInstitute of Animal Physiology and Genetics, the Czech Academy of Sciences, Libechov, Czech Republic.
Jana CizkovaInstitute of Animal Physiology and Genetics, the Czech Academy of Sciences, Libechov, Czech Republic.
Vratislav HorakInstitute of Animal Physiology and Genetics, the Czech Academy of Sciences, Libechov, Czech Republic.
Czech Academy of Sciences, Institute of Animal Physiology and Genetics · CZCzech University of Life Sciences Prague · CZFakultní nemocnice Bulovka · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimSpontaneous regression (SR) of tumours is a rare phenomenon not yet fully understood. The aim of this study was to investigate immune cells infiltrating progressive and SR tumours in a Lewis rat sarcoma model. MATERIALS AND

methodsRats were subcutaneously inoculated with rat sarcoma R5-28 (clone C4) cells. Developing tumours were obtained on day 42 and cryosections were immunohistochemically processed for detection of immune cells.

resultsA high density of granulocytes was found in the necrotic areas of both progressive and SR tumours. CD4

conclusionBased on the differences in number and distribution of the immune cell subpopulations, we believe that natural killer (CD161

Indexed as

AnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesDisease Models, AnimalGene Expression Regulation, NeoplasticHumansImmunohistochemistryKiller Cells, NaturalNeoplasm Regression, SpontaneousNK Cell Lectin-Like Receptor Subfamily BRatsRats, Inbred LewSarcomaNK Cell Lectin-Like Receptor Subfamily BCD161CD4CD8immunohistochemistryspontaneous regressionTumour

Identifiers

PMID30587601
PMCPMC6364084
OpenAlexW2906430348

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.