Evidence map›Paper›PMID 30587587›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Two separate functions of NME3 critical for cell survival underlie a neurodegenerative disorder.

Chih-Wei Chen, Hong-Ling Wang, Ching-Wen Huang, Chang-Yu Huang, Wai Keong Lim, I-Chen Tu, Atmaja Koorapati, Sung-Tsang Hsieh, Hung-Wei Kan, Shiou-Ru Tzeng and 14 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Functional Diversity and Emerging Roles of Human NME/NDPK Group II Proteins.International journal of molecular sciences · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Science translational medicine · 2024
    Article
  13. Review
  14. Histidine Phosphorylation: Protein Kinases and Phosphatases.International journal of molecular sciences · 2024
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 9 institutions in 2 countries.

Chih-Wei ChenInstitute of Molecular Medicine, College of Medicine, National Taiwan University, 10002 Taipei, Taiwan.ORCID 0000-0002-1401-4820
Hong-Ling WangInstitute of Molecular Medicine, College of Medicine, National Taiwan University, 10002 Taipei, Taiwan.
Ching-Wen HuangDepartment of Medicine, College of Medicine, National Taiwan University, 10002 Taipei, Taiwan.
Chang-Yu HuangInstitute of Biochemistry and Molecular Biology, National Yang-Ming University, 11221 Taipei, Taiwan.ORCID 0000-0001-7430-2085
Wai Keong LimInstitute of Molecular Medicine, College of Medicine, National Taiwan University, 10002 Taipei, Taiwan.
I-Chen TuInstitute of Molecular Medicine, College of Medicine, National Taiwan University, 10002 Taipei, Taiwan.
Atmaja KoorapatiInstitute of Molecular Medicine, College of Medicine, National Taiwan University, 10002 Taipei, Taiwan.
Sung-Tsang HsiehInstitute of Anatomy and Cell Biology, College of Medicine, National Taiwan University, 10002 Taipei, Taiwan.
Hung-Wei KanInstitute of Anatomy and Cell Biology, College of Medicine, National Taiwan University, 10002 Taipei, Taiwan.
Shiou-Ru TzengInstitute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, 10002 Taipei, Taiwan.
Jung-Chi LiaoInstitute of Atomic and Molecular Sciences, Academia Sinica, 10617 Taipei, Taiwan.ORCID 0000-0002-4323-6318
Weng Man ChongInstitute of Atomic and Molecular Sciences, Academia Sinica, 10617 Taipei, Taiwan.
Inna NaroditzkyDepartment of Pathology, Rambam Health Care Campus, 31096 Haifa, Israel.
Dvora KidronDepartment of Pathology, Meir Hospital, 44100 Kfar Saba, Israel.
Ayelet EranDepartment of Radiology, Rambam Health Care Campus, 31096 Haifa, Israel.
Yousif NijimPediatric and Neonatal Unit, Nazareth Hospital EMMS, 17639 Nazareth, Israel.
Ella SelaPediatric and Neonatal Unit, Nazareth Hospital EMMS, 17639 Nazareth, Israel.
Hagit Baris FeldmanThe Genetics Institute, Rambam Health Care Campus, 31096 Haifa, Israel.
Limor KalfonInstitute of Human Genetics, Galilee Medical Center, 22100 Nahariya, Israel.
Hadas Raveh-BarakInstitute of Human Genetics, Galilee Medical Center, 22100 Nahariya, Israel.
Tzipora C Falik-ZaccaiInstitute of Human Genetics, Galilee Medical Center, 22100 Nahariya, Israel.
Orly ElpelegDepartment of Genetic and Metabolic Diseases, Hadassah Hebrew University Medical Center, 91120 Jerusalem, Israel.
Hanna MandelInstitute of Human Genetics, Galilee Medical Center, 22100 Nahariya, Israel; h_mandel@rambam.health.gov.il zfchang@ntu.edu.tw.
Zee-Fen ChangInstitute of Molecular Medicine, College of Medicine, National Taiwan University, 10002 Taipei, Taiwan; h_mandel@rambam.health.gov.il zfchang@ntu.edu.tw.
National Taiwan University · TWRambam Health Care Campus · ILWestern Galilee Hospital · ILInstitute of Atomic and Molecular Sciences, Academia Sinica · TWNational Yang Ming Chiao Tung University · TWNazareth Hospital EMMS · ILBar-Ilan University · ILHadassah Medical Center · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a patient who presented with congenital hypotonia, hypoventilation, and cerebellar histopathological alterations. Exome analysis revealed a homozygous mutation in the initiation codon of the

Indexed as

Adenosine TriphosphateHomozygoteNeurodegenerative DiseasesNM23 Nucleoside Diphosphate KinasesCell LineCell SurvivalEnergy MetabolismFemaleHumansMaleMitochondriaMitochondrial DynamicsAdenosine TriphosphateNM23 Nucleoside Diphosphate KinasesNME3 protein, humanmetabolic adaptationmitochondrial fusionNDP kinaseneurodegenerationNME3

Identifiers

PMID30587587
PMCPMC6329951
OpenAlexW2907269833

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.