Evidence map›Paper›PMID 30587577›Full record

ArticleThe Journal of biological chemistry2019

Dephosphorylation of human dopamine transporter at threonine 48 by protein phosphatase PP1/2A up-regulates transport velocity.

Jae-Won Yang, Garret Larson, Lisa Konrad, Madhur Shetty, Marion Holy, Kathrin Jäntsch, Mirja Kastein, Seok Heo, Fatma Asli Erdem, Gert Lubec and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Platelets mirror changes in the frontal lobe antioxidant system in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Jae-Won YangFrom the Institute of Pharmacology, Center for Physiology and Pharmacology, and.ORCID 0000-0001-8928-0130
Garret Larsonthe Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota 58202-9037, and.
Lisa KonradFrom the Institute of Pharmacology, Center for Physiology and Pharmacology, and.
Madhur Shettythe Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota 58202-9037, and.
Marion HolyFrom the Institute of Pharmacology, Center for Physiology and Pharmacology, and.
Kathrin JäntschFrom the Institute of Pharmacology, Center for Physiology and Pharmacology, and.
Mirja KasteinFrom the Institute of Pharmacology, Center for Physiology and Pharmacology, and.
Seok Heothe Department of Pediatrics, Medical University of Vienna, 1090 Vienna, Austria.
Fatma Asli ErdemFrom the Institute of Pharmacology, Center for Physiology and Pharmacology, and.
Gert LubecParacelsus Medical University of Salzburg, 5020 Salzburg, Austria.
Roxanne A Vaughanthe Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota 58202-9037, and.
Harald H SitteFrom the Institute of Pharmacology, Center for Physiology and Pharmacology, and harald.sitte@meduniwien.ac.at.ORCID 0000-0002-1339-7444
James D Fosterthe Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota 58202-9037, and james.d.foster@med.und.edu.
Pharmacology Research Institute · USUniversity of North Dakota · USMedical University of Vienna · ATMED Institute · USUniversity of Salzburg · AT

Funding

Research CoresP20GM103442 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI Chris Jurgens · 2012 to 2026
$53.0M
The role of class IIa Hdac in regulating cell fate choice in early cortical development.P20GM104360 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI VAUGHAN, ROXANNE A · 2013 to 2023
$21.1M
Phosphorylation and Regulation of Dopamine TransportersR01DA013147 · NIDA · UNIVERSITY OF NORTH DAKOTA · PI VAUGHAN, ROXANNE A · 1999 to 2010
$2.5M
Dopamine Transporter PalmitoylationR15DA031991 · NIDA · UNIVERSITY OF NORTH DAKOTA · PI FOSTER, JAMES DARREN · 2011 to 2017
$823k
NIDA NIH HHS R01 DA013147NIDA NIH HHS R15 DA031991NIGMS NIH HHS P20 GM103442NIGMS NIH HHS P20 GM104360
6 · The paper itself

Abstract

Several protein kinases, including protein kinase C, Ca

Indexed as

AnimalsBiological Transport, ActiveBrainDopamineDopamine Plasma Membrane Transport ProteinsHumansLipoylationMiceMice, KnockoutPhosphorylationProtein Phosphatase 1Protein Phosphatase 2ThreonineDopamineDopamine Plasma Membrane Transport ProteinsProtein Phosphatase 1Protein Phosphatase 2Threoninedephosphorylationdopamine transportermass spectrometry (MS)neurotransmissionokadaic acidpalmitoylationphosphorylationpost-translational modification (PTM)protein phosphataseprotein-protein interactionsynaptic transmission

Identifiers

PMID30587577
PMCPMC6416449
OpenAlexW2908161923

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.