Evidence map›Paper›PMID 30587560›Full record

ArticleClinical medicine & research2018

Metastatic Prostate Cancer in a

Bindu R Potugari, Jessica M Engel, Adedayo A Onitilo

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical medicine & research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Journal of oncology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Bindu R PotugariDepartment of Internal Medicine, Marshfield Clinic, Marshfield, Wisconsin, USA.
Jessica M EngelDepartment of Hematology/Oncology, Marshfield Clinic, Weston, Wisconsin, USA.
Adedayo A OnitiloDepartment of Hematology/Oncology, Marshfield Clinic, Weston, Wisconsin, USA onitilo.adedayo@marshfieldclinic.org.
Marshfield Clinic Weston Center · USMarshfield Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A man, aged 61 years, with a history of hypogonadism and family history of cancer experienced persistent urinary difficulties with no visible prostate abnormalities. Laboratory testing and diagnostic imaging revealed a primary lesion in the prostate with lymph node involvement and multiple bone metastases. Treatment with androgen-deprivation therapy, 17,20-lyase inhibition, and bisphosphonates for 7 months was unsuccessful in preventing disease progression, but second-line chemotherapy and continued androgen-deprivation therapy improved prostate specific antigen levels. During the patient's second treatment regimen, his daughter received a diagnosis of breast cancer. The patient's daughter underwent genetic testing for oncogenic mutations, and it was discovered that she carried a mutation in

Indexed as

MutationAntineoplastic Combined Chemotherapy ProtocolsDNA-Binding ProteinsDNA RepairHumansMaleMiddle AgedNeoplasm MetastasisProstatic NeoplasmsDNA-Binding ProteinsRAD51C protein, humanMetastaticProstate cancerRAD51C

Identifiers

PMID30587560
PMCPMC6306144
OpenAlexW2907622575

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.