ArticleBMC immunology2018
Variation in IL-21-secreting circulating follicular helper T cells in Kawasaki disease.
Article in BMC immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 7 citations in OpenAlex.
- Overview of T-cell subsets and related cytokines in Kawasaki disease.Pediatric research · 2026Review
- Immunophenotype of Kawasaki Disease: Insights into Pathogenesis and Treatment Response.Life (Basel, Switzerland) · 2025Review
- Predictors of mortality in patients with COVID-19 by flow cytometry.Clinical immunology communications · 2023Article
- Frequency of Efficient Circulating Follicular Helper T Cells Correlates with Dyslipidemia and WBC Count in Atherosclerosis.Iranian biomedical journal · 2021Article
- Kawasaki syndrome: role of superantigens revisited.The FEBS journal · 2021Review
- Peripheral follicular cytotoxic T -like cells in Kawasaki disease with coronary artery aneurysms: A case report.Medicine · 2020Article
- Distinct variations of antibody secreting cells and memory B cells during the course of Kawasaki disease.BMC immunology · 2019Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveCirculating follicular helper T (cTfh) cells are a specialized subset of CD4
methodsAccording to the differential expression of inducible co-stimulator (ICOS) and programmed cell death protein 1 (PD-1), cTfh cells were divided into distinct subsets. We used flow cytometry and flow cytometric bead arrays (CBA) to analyze subsets of CD4
resultsIn the acute phase (AP), the percentages of ICOS
conclusionsThe present study is the first investigation that examined the distribution of circulating cTfh cell subsets in Kawasaki disease. Both cTfh cells and serum IL-21 are essential to the pathogenesis of KD. Our study provides further understanding of the immune response involved in KD and offers novel insights in the pathogenetic mechanism of this disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.