Evidence map›Paper›PMID 30586949›Full record

ArticleMolecules (Basel, Switzerland)2018

Dermal Delivery of Selected Polyphenols from Silybum marianum. Theoretical and Experimental Study.

Pavel Kosina, Markéta Paloncýová, Alena Rajnochová Svobodová, Bohumil Zálešák, David Biedermann, Jitka Ulrichová, Jitka Vostálová

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Pavel KosinaDepartment of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech Republic. pavel.kosina@upol.cz.ORCID 0000-0003-1991-1990
Markéta PaloncýováRegional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University, tř. 17 listopadu 12, 771 46 Olomouc, Czech Republic. marketa.paloncyova@upol.cz.ORCID 0000-0002-6811-7761
Alena Rajnochová SvobodováDepartment of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech Republic. alena.rajnochova@upol.cz.
Bohumil ZálešákDepartment of Plastic and Aesthetic Surgery, University Hospital Olomouc, I. P. Pavlova 6, 779 00 Olomouc, Czech Republic. bohumil.zalesak@fnol.cz.
David BiedermannInstitute of Microbiology, Laboratory of Biotransformation, Academy of Sciences of the Czech Republic, Vídeňská 1083, 142 20 Prague, Czech Republic. biedermann@biomed.cas.cz.ORCID 0000-0001-6726-9301
Jitka UlrichováDepartment of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech Republic. jitka.ulrichova@upol.cz.
Jitka VostálováDepartment of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech Republic. jitka.vostalova@upol.cz.ORCID 0000-0003-0948-0891
Palacký University Olomouc · CZCzech Academy of Sciences · CZRegional Centre of Advanced Technologies and Materials · CZUniversity Hospital Olomouc · CZ

Funding

Grantová Agentura České Republiky 15-10897SGrantová Agentura České Republiky P208/12/G016Univerzita Palackého v Olomouci RVO 61989592
6 · The paper itself

Abstract

Silymarin is a well-known standardized extract from the seeds of milk thistle (

Indexed as

Drug Delivery SystemsDermisHumansHydrophobic and Hydrophilic InteractionsPermeabilityPolyphenolsSilybum marianumThermodynamicsPolyphenolsexperimental and computational hydrophobicityflavonoidsflavonolignansSilybum marianumskin intaketheoretical lipid membrane models

Identifiers

PMID30586949
PMCPMC6337146
OpenAlexW2905927716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.