Evidence map›Paper›PMID 30586934›Full record

ArticleMarine drugs2018

UPLC⁻MS/MS Identification of Sterol Sulfates in Marine Diatoms.

Genoveffa Nuzzo, Carmela Gallo, Giuliana d'Ippolito, Emiliano Manzo, Nadia Ruocco, Ennio Russo, Ylenia Carotenuto, Maria Costantini, Valerio Zupo, Angela Sardo and 1 more

Open access · goldAbstract readValidation Study
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Cell-Death Metabolites fromMarine drugs · 2024
    Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Genoveffa NuzzoBio-Organic Chemistry Unit, Institute of Biomolecular Chemistry CNR, Via Campi Flegrei 34, Pozzuoli, 80078 Naples, Italy. nuzzo.genoveffa@icb.cnr.it.ORCID 0000-0001-7065-2379
Carmela GalloBio-Organic Chemistry Unit, Institute of Biomolecular Chemistry CNR, Via Campi Flegrei 34, Pozzuoli, 80078 Naples, Italy. carmen.gallo@icb.cnr.it.ORCID 0000-0002-1665-2615
Giuliana d'IppolitoBio-Organic Chemistry Unit, Institute of Biomolecular Chemistry CNR, Via Campi Flegrei 34, Pozzuoli, 80078 Naples, Italy. gdippolito@icb.cnr.it.ORCID 0000-0002-1665-2615
Emiliano ManzoBio-Organic Chemistry Unit, Institute of Biomolecular Chemistry CNR, Via Campi Flegrei 34, Pozzuoli, 80078 Naples, Italy. emanzo@icb.cnr.it.
Nadia RuoccoBio-Organic Chemistry Unit, Institute of Biomolecular Chemistry CNR, Via Campi Flegrei 34, Pozzuoli, 80078 Naples, Italy. nadia.ruocco@gmail.com.
Ennio RussoDepartment of Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Napoli, Italy. ennio.erre@gmail.com.
Ylenia CarotenutoDepartment of Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Napoli, Italy. ylenia@szn.it.
Maria CostantiniDepartment of Marine Biotechnology, Stazione Zoologica Anton Dohrn, 80121 Naples, Italy. mcosta@szn.it.
Valerio ZupoDepartment of Marine Biotechnology, Stazione Zoologica Anton Dohrn, 80121 Naples, Italy. vzupo@szn.it.
Angela SardoBio-Organic Chemistry Unit, Institute of Biomolecular Chemistry CNR, Via Campi Flegrei 34, Pozzuoli, 80078 Naples, Italy. angela.sardo@icb.cnr.it.
Angelo FontanaBio-Organic Chemistry Unit, Institute of Biomolecular Chemistry CNR, Via Campi Flegrei 34, Pozzuoli, 80078 Naples, Italy. afontana@icb.cnr.it.
Stazione Zoologica Anton Dohrn · IT

Funding

SIBAFEQ project PON01_02740
6 · The paper itself

Abstract

Diatoms are unicellular eukaryotic organisms that play a key ecological and biogeochemical role in oceans as major primary producers. Recently, these microalgae have also attracted interest as a promising source of functional products with widespread relevance. Progress in the knowledge of cell and molecular biology of diatoms is envisaged as a key step to understanding regulation of their life cycle in marine environments as well as facilitating their full and profitable exploitation by biotechnological platforms. Recently, we identified sterol sulfates (StS) as regulatory molecules of cell death in the diatom

Indexed as

Chemical FractionationChromatography, High Pressure LiquidChromatography, Reverse-PhaseDiatomsLimit of DetectionMicroalgaeReproducibility of ResultsSensitivity and SpecificitySpecies SpecificitySterolsSulfatesTandem Mass SpectrometrySterolsSulfateschromatographydiatomdinoflagellatemarine organismmass spectrometrynatural productsecondary metabolitesterolsulfotransferaseterpene

Identifiers

PMID30586934
PMCPMC6356472
OpenAlexW2905651113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.