Evidence map›Paper›PMID 30586863›Full record

ArticleInternational journal of molecular sciences2018

Periostin Mediates Right Ventricular Failure through Induction of Inducible Nitric Oxide Synthase Expression in Right Ventricular Fibroblasts from Monocrotaline-Induced Pulmonary Arterial Hypertensive Rats.

Keisuke Imoto, Muneyoshi Okada, Hideyuki Yamawaki

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Signaling pathways and targeted therapy for pulmonary hypertension.Signal transduction and targeted therapy · 2025
    Review
  3. Review
  4. Article
  5. Serum Periostin Levels in Acute Myocardial Infarction Patients: a 3-month Follow-up Study.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2023
    Article
  6. Periostin: an emerging activator of multiple signaling pathways.Journal of cell communication and signaling · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. A single injection of periostin decreases cardiac voltage-gated NaThe Journal of veterinary medical science · 2021
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Keisuke ImotoLaboratory of Veterinary Pharmacology, School of Veterinary Medicine, Kitasato University, Higashi 23 bancho 35-1, Towada City, Aomori 034-8628, Japan. dv16001@st.kitasato-u.ac.jp.
Muneyoshi OkadaLaboratory of Veterinary Pharmacology, School of Veterinary Medicine, Kitasato University, Higashi 23 bancho 35-1, Towada City, Aomori 034-8628, Japan. mokada@vmas.kitasato-u.ac.jp.
Hideyuki YamawakiLaboratory of Veterinary Pharmacology, School of Veterinary Medicine, Kitasato University, Higashi 23 bancho 35-1, Towada City, Aomori 034-8628, Japan. yamawaki@st.kitasato-u.ac.jp.
Kitasato University · JP

Funding

Japan Society for the Promotion of Science 18J11540
6 · The paper itself

Abstract

Pulmonary arterial hypertension (PAH) leads to lethal right ventricular failure (RVF). Periostin (

Indexed as

AnimalsCalciumCalcium Channels, L-TypeCell Adhesion MoleculesFibroblastsHeart VentriclesHypertension, PulmonaryJNK Mitogen-Activated Protein KinasesMaleMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3MonocrotalineNF-kappa BNitric OxideNitric Oxide Synthase Type IIRatsCalciumCalcium Channels, L-TypeCell Adhesion MoleculesJNK Mitogen-Activated Protein KinasesMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3MonocrotalineNF-kappa BNitric OxideNitric Oxide Synthase Type IIPostn protein, ratRecombinant Proteinsinducible nitric oxide synthase">l-type Ca2+ channelmonocrotalinenitric oxideperiostinpulmonary arterial hypertensionright ventricular failureright ventricular fibroblasts

Identifiers

PMID30586863
PMCPMC6337160
OpenAlexW2906215263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.