Evidence map›Paper›PMID 30586505›Full record

ArticleThe New England journal of medicine2018

Worldwide Frequencies of APOL1 Renal Risk Variants.

Girish N Nadkarni, Christopher R Gignoux, Elena P Sorokin, Michelle Daya, Rayees Rahman, Kathleen C Barnes, Christina L Wassel, Eimear E Kenny

Abstract readLetter
In one paragraph

Article in The New England journal of medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Update on APOL1 and chronic kidney diseases in children.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Kidney medicine · 2025
    Review
  12. Review
  13. Article
  14. Practical Considerations for Sharing Race-Based Genetic Research Findings.Journal of the American Society of Nephrology : JASN · 2025
    Article
  15. Article
  16. Multiethnic prevalence of theClinical kidney journal · 2025
    Article
  17. Review
  18. Article
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Girish N NadkarniIcahn School of Medicine at Mount Sinai, New York, NY.
Christopher R GignouxUniversity of Colorado Anschutz Medical Campus, Aurora, CO.
Elena P SorokinSchool of Medicine at Stanford University, Stanford, CA.
Michelle DayaUniversity of Colorado Anschutz Medical Campus, Aurora, CO.
Rayees RahmanIcahn School of Medicine at Mount Sinai, New York, NY.
Kathleen C BarnesUniversity of Colorado Anschutz Medical Campus, Aurora, CO.
Christina L WasselLarner College of Medicine at the University of Vermont, Burlington, VT.
Eimear E KennyIcahn School of Medicine at Mount Sinai, New York, NY eimear.kenny@mssm.edu.

Funding

New Approaches for Empowering Studies of Asthma in Populations of African DescentR01HL104608 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI BARNES, KATHLEEN C, KENNY, EIMEAR ELIZABETH · 2011 to 2022
$23.1M
Teaching biomedical and pharmacological trainees to produce FAIR data for AI & ML applicationsT32GM062754 · NIGMS · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI SCHLESSINGER, AVNER · 2001 to 2023
$6.2M
Optimizing imputation for diverse populations in a distributed frameworkU01HG009080 · NHGRI · STANFORD UNIVERSITY · PI KENNY, EIMEAR ELIZABETH · 2016 to 2020
$5.2M
Transforming Genomics with 5 PB Big Omics Data Engine Cray CS300-AC SupercomputerS10OD018522 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2014 to 2014
$1.9M
Risk Clustering and Stratification in Genetically High-Risk Individuals Using Electronic Medical Records and BiomarkersK23DK107908 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI NADKARNI, GIRISH NITIN · 2016 to 2020
$930k
NHGRI NIH HHS U01 HG009080NHLBI NIH HHS R01 HL104608NIDDK NIH HHS K23 DK107908NIGMS NIH HHS T32 GM062754NIH HHS S10 OD018522
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic VariationApolipoprotein L1Black or African AmericanGenetic Predisposition to DiseaseGenotypeHumansKidney DiseasesRiskAPOL1 protein, humanApolipoprotein L1

Identifiers

PMID30586505
PMCPMC6482949

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.