Evidence map›Paper›PMID 30586453›Full record

ArticlePloS one2018

Veterans have greater variability in their perception of binocular alignment.

Michael C Schubert, Yoav Gimmon, Jennifer Millar, Kelly J Brewer, Dale Roberts, Mark Shelhamer, Charles Rohde, Jorge M Serrador

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Binocular Alignment Changes Between Sitting and Supine Positions in Patients with Dizziness.Journal of the Association for Research in Otolaryngology : JARO · 2022
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael C SchubertLaboratory of Vestibular NeuroAdaptation, Department of Otolaryngology-Head and Neck Surgery Baltimore, MD, United States of America.ORCID 0000-0002-5975-374X
Yoav GimmonLaboratory of Vestibular NeuroAdaptation, Department of Otolaryngology-Head and Neck Surgery Baltimore, MD, United States of America.
Jennifer MillarDepartment of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
Kelly J BrewerWar Related Illness and Injury Study Center, Department of Veteran Affairs, NJ, United States of America.
Dale RobertsDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
Mark ShelhamerLaboratory of Vestibular NeuroAdaptation, Department of Otolaryngology-Head and Neck Surgery Baltimore, MD, United States of America.
Charles RohdeBloomberg School of Public Health, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
Jorge M SerradorWar Related Illness and Injury Study Center, Department of Veteran Affairs, NJ, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionA significant population of our wounded veterans suffer long-term functional consequences of visual deficit, disorientation, dizziness, and an impaired ability to read. These symptoms may be related to damage within the otolith pathways that contribute to ocular alignment. The purpose of this study was to compare perception of vertical and torsional ocular alignment between veterans and healthy controls in an upright and supine test position. MATERIALS AND

methodsVeterans (n = 26) with reports of dizziness were recruited from the East Orange Veterans Administration Hospital. Healthy controls (n = 26) were recruited from both Johns Hopkins University and the East Orange VA. Each subject performed 20 trials each of a novel vertical and torsional binocular alignment perception test. Veterans underwent semicircular canal and otolith pathway function testing.

results88% of the Veterans had an absent otolith response. Only the veterans had an abnormally large variability in perception of both vertical and torsional ocular alignment, and in both upright and supine position. Neither post-traumatic stress disorder, nor depression contributed to the misperception in binocular alignment.

conclusionsOur novel method of measuring vertical and torsional misalignment distinguishes veterans with dizziness from healthy controls. The high prevalence of absent otolith function seems to explain this result. Further studies are needed to better understand the fundamental mechanism responsible for the increased variability of perception of binocular alignment.

Indexed as

DizzinessEyeEye MovementsFemaleHumansMaleMiddle AgedOtolithic MembraneReflex, Vestibulo-OcularStress Disorders, Post-TraumaticVertigoVeteransVision, BinocularVision Disorders

Identifiers

PMID30586453
PMCPMC6306227

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.