Evidence map›Paper›PMID 30586413›Full record

ArticlePloS one2018

The genus Borrelia reloaded.

Gabriele Margos, Alex Gofton, Daniel Wibberg, Alexandra Dangel, Durdica Marosevic, Siew-May Loh, Charlotte Oskam, Volker Fingerle

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  5. Molecular identification ofParasite epidemiology and control · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Borrelia surface proteins: new horizons in Lyme disease diagnosis.Applied microbiology and biotechnology · 2025
    Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Systematic investigation of theOne health (Amsterdam, Netherlands) · 2024
    Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Gabriele MargosBavarian Health and Food Safety Authority and National Reference Center for Borrelia, Oberschleissheim, Germany.ORCID 0000-0001-5304-9615
Alex GoftonVector & Waterborne Pathogens Research Group, School of Veterinary & Life Sciences, Murdoch University, South St, Murdoch, Australia.
Daniel WibbergCebitec, University of Bielefeld, Bielefeld, Germany.
Alexandra DangelBavarian Health and Food Safety Authority and National Reference Center for Borrelia, Oberschleissheim, Germany.
Durdica MarosevicBavarian Health and Food Safety Authority and National Reference Center for Borrelia, Oberschleissheim, Germany.
Siew-May LohVector & Waterborne Pathogens Research Group, School of Veterinary & Life Sciences, Murdoch University, South St, Murdoch, Australia.
Charlotte OskamVector & Waterborne Pathogens Research Group, School of Veterinary & Life Sciences, Murdoch University, South St, Murdoch, Australia.ORCID 0000-0001-8886-2120
Volker FingerleBavarian Health and Food Safety Authority and National Reference Center for Borrelia, Oberschleissheim, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genus Borrelia, originally described by Swellengrebel in 1907, contains tick- or louse-transmitted spirochetes belonging to the relapsing fever (RF) group of spirochetes, the Lyme borreliosis (LB) group of spirochetes and spirochetes that form intermittent clades. In 2014 it was proposed that the genus Borrelia should be separated into two genera; Borrelia Swellengrebel 1907 emend. Adeolu and Gupta 2014 containing RF spirochetes and Borreliella Adeolu and Gupta 2014 containing LB group of spirochetes. In this study we conducted an analysis based on a method that is suitable for bacterial genus demarcation, the percentage of conserved proteins (POCP). We included RF group species, LB group species and two species belonging to intermittent clades, Borrelia turcica Güner et al. 2004 and Candidatus Borrelia tachyglossi Loh et al. 2017. These analyses convincingly showed that all groups of spirochetes belong into one genus and we propose to emend, and re-unite all groups in, the genus Borrelia.

Indexed as

AnimalsBorreliaBorrelia InfectionsDNA, BacterialHost Microbial InteractionsHost SpecificityHumansLyme DiseasePhylogenyRelapsing FeverSequence Analysis, DNADNA, Bacterial

Identifiers

PMID30586413
PMCPMC6306154

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.