Evidence map›Paper›PMID 30586373›Full record

ArticlePloS one2018

Reliability of information about the use of antiepileptic drugs during pregnancy from three major web search engines in China.

Xi Zhu, Xiangmiao Qiu, Dingwang Wu, Shidong Chen, Jiwen Xiong, Hongxuan Du, Zihao Dai, Jamy Hoang, Anjiao Peng, Shixu He and 2 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Xi ZhuDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.
Xiangmiao QiuDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.
Dingwang WuDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.
Shidong ChenDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.
Jiwen XiongDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.
Hongxuan DuDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.
Zihao DaiDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.
Jamy HoangDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.
Anjiao PengDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.
Shixu HeDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.
Jianan DuanDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.
Lei ChenDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.ORCID 0000-0001-5263-5540
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objective of this study was to assess the reliability of online information, as provided by three major search engines in China, about the usage of antiepileptic drugs (AEDs) during pregnancy.

methodOver eight weeks, six physicians conducted a literature search on six computers and six smartphones at a frequency of once per week. During each web search on each computer and smartphone, three major search engines in China were used, namely, Baidu, Sogou and 360. The search terms used were a combination of words, including one AED name (valproate/oxcarbazepine/levetiracetam/lamotrigine) and one Chinese word ("huaiyun" or "renshen", which means pregnancy in Chinese). The top ten websites retrieved from each search were recorded. After the content of each website was evaluated, the sites were categorized into 9 types. Meanwhile, commercial advertisements on each web page were also registered.

resultsA total of 16,411 search results were assessed. After excluding the redundant web pages, 4840 search results were included in the data analysis. Only 12.05% of the search results were reliable, 47.75% were partly reliable, and 40.21% were unreliable. A total of 4139 (85.52%) webpages contained commercial advertisements. The results from a multivariate analysis suggested that websites with no advertisements and professional websites have an independent positive impact on reliability.

conclusionOverall, little information on AED usage during pregnancy provided by major search engines in China was reliable. PRACTICE IMPLICATIONS: Accurate and professional online information for female patients with epilepsy should be provided through major efforts by the government, search engine companies, professional websites and epilepsy physicians.

Indexed as

Health EducationInternetSearch EngineAnticonvulsantsChinaFemaleHumansPregnancyPregnancy ComplicationsReproducibility of ResultsAnticonvulsants

Identifiers

PMID30586373
PMCPMC6306163
OpenAlexW2905898060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.