Evidence map›Paper›PMID 30586354›Full record

Trial reportPloS one2018

Barriers and facilitators to the uptake of Test and Treat in Mozambique: A qualitative study on patient and provider perceptions.

Pedroso Nhassengo, Fabian Cataldo, Amilcar Magaço, Risa M Hoffman, Lucas Nerua, Mohomede Saide, Rosa Cuco, Roxanne Hoek, Francisco Mbofana, Aleny Couto and 3 more

Abstract readClinical TrialMulticenter Study
In one paragraph

Trial report in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Pedroso NhassengoHealth System Research Sector, National Institute of Health, Maputo, Mozambique.
Fabian CataldoInstitute for Global Health and Development, Queen Margaret University, Edinburgh, United Kingdom.ORCID 0000-0001-8980-8951
Amilcar MagaçoHealth System Research Sector, National Institute of Health, Maputo, Mozambique.
Risa M HoffmanDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America.ORCID 0000-0001-9575-4574
Lucas NeruaHealth System Research Sector, National Institute of Health, Maputo, Mozambique.
Mohomede SaideHealth System Research Sector, National Institute of Health, Maputo, Mozambique.
Rosa CucoNational STI-HIV/AIDS Program, Ministry of Health, Maputo, Mozambique.ORCID 0000-0003-1589-7044
Roxanne HoekNational STI-HIV/AIDS Program, Ministry of Health, Maputo, Mozambique.
Francisco MbofanaNational Council against HIV/AIDS, Maputo, Mozambique.
Aleny CoutoNational STI-HIV/AIDS Program, Ministry of Health, Maputo, Mozambique.
Eduardo GudoHealth System Research Sector, National Institute of Health, Maputo, Mozambique.ORCID 0000-0002-8686-7873
Sergio ChicumbeHealth System Research Sector, National Institute of Health, Maputo, Mozambique.
Kathryn DovelDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America.ORCID 0000-0002-5622-3401

Funding

Virology CoreP30AI028697 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ANTON, PETER A · 1991 to 2018
$39.9M
Postdoctoral Training in Global AIDS Prevention ResearchT32MH080634 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JESSE LAWTON CLARK, Pamina Mae Gorbach · 2007 to 2026
$6.4M
NIAID NIH HHS P30 AI028697NIMH NIH HHS L30 MH114321NIMH NIH HHS T32 MH080634PEPFAR
6 · The paper itself

Abstract

backgroundIn mid-2016, Mozambique began phased implementation of the 'Test-and-Treat' policy, which enrolls HIV positive clients into antiretroviral treatment (ART) immediately regardless of CD4 cell count or disease stage. Novel insights into barriers and facilitators to ART initiation among healthy clients are needed to improve implementation of Test and Treat. METHODS AND

findingsA cross-sectional qualitative study was conducted across 10 health facilities in Mozambique. In-depth interviews (IDIs) were conducted with HIV-positive clients (60 who initiated/20 who did not initiate ART within Test and Treat) and 9 focus group discussion (FGDs) were conducted with health care workers (HCWs; n = 53). Data were analyzed using deductive and inductive analysis strategies. Barriers to ART initiation included: (1) feeling 'healthy'; (2) not prepared to start ART for life; (3) concerns about ART side effects; (4) fear of HIV disclosure and discrimination; (5) poor interactions with HCWs; (6) limited privacy at health facilities; and (7) perceptions of long wait times. Facilitators included the motivation to stay healthy and to take care of dependents, as well as new models of ART services such as adaptation of counseling to clients' specific needs, efficient patient flow, and integrated HIV/primary care services.

conclusionsART initiation may be difficult for healthy clients in the context of Test-and-Treat. Specific strategies to engage this population are needed. Strategies could include targeted support for clients, community sensitization on the benefits of early ART initiation, client-centered approaches to patient care, and improved efficiency through multi-month scripting and increased workforce.

Indexed as

Attitude of Health PersonnelAttitude to HealthPerceptionAdolescentAdultAnti-Retroviral AgentsCD4 Lymphocyte CountCross-Sectional StudiesFemaleHIV SeropositivityHumansMaleMiddle AgedMozambiqueAnti-Retroviral Agents

Identifiers

PMID30586354
PMCPMC6306230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.