Evidence map›Paper›PMID 30586353›Full record

ArticlePloS one2018

Measuring asymmetry from high-density 3D surface scans: An application to human faces.

Omid Ekrami, Peter Claes, Julie D White, Arslan A Zaidi, Mark D Shriver, Stefan Van Dongen

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Streamlining asymmetry quantification in fetal mouse imaging: A semi-automated pipeline supported by expert guidance.Developmental dynamics : an official publication of the American Association of Anatomists · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Effects of Male Facial Masculinity on Perceived Attractiveness.Adaptive human behavior and physiology · 2021
    Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Omid EkramiEvolutionary Ecology Group, Department of Biology, University of Antwerp, Antwerp, Belgium.ORCID 0000-0002-6135-8693
Peter ClaesMedical Imaging Research Center (MIRC), Department of Electrical Engineering-ESAT, Faculty of Engineering, KU Leuven, Leuven, Belgium.
Julie D WhiteDepartment of Anthropology, The Pennsylvania State University, University Park, Pennsylvania, United States of America.
Arslan A ZaidiDepartment of Anthropology, The Pennsylvania State University, University Park, Pennsylvania, United States of America.
Mark D ShriverDepartment of Anthropology, The Pennsylvania State University, University Park, Pennsylvania, United States of America.
Stefan Van DongenEvolutionary Ecology Group, Department of Biology, University of Antwerp, Antwerp, Belgium.
Pennsylvania State University · USUniversity of Antwerp · BEKU Leuven · BE

Funding

The Genetic Architecture of Human Facial MorphologyR01DE027023 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CLAES, PETER, SHAFFER, JOHN R · 2017 to 2024
$5.2M
NIDCR NIH HHS R01 DE027023
6 · The paper itself

Abstract

Perfect bilateral symmetry is the optimal outcome of the development of bilateral traits in the absence of developmental perturbations. Any random perturbation in this perfect symmetrical state is called Fluctuating Asymmetry (FA). Many studies have been conducted on FA as an indicator of Developmental Instability (DI) and its possible link with stress and individual quality in general and with attractiveness, health and level of masculinity or femininity in humans. Most human studies of facial asymmetry use 2D pictures and a limited number of landmarks. We developed a protocol to utilize high-density 3D scans of human faces to measure the level of asymmetry. A completely symmetric spatially dense anthropometric mask with paired vertices is non-rigidly mapped on target faces using an Iterative Closest Point (ICP) registration algorithm. A set of 19 manually indicated landmarks were used to validate the mapping precision. The protocol's accuracy in FA calculation is assessed, and results show that a spatially dense approach is more accurate. In addition, it generates an integrated asymmetry estimate across the entire face. Finally, the automatic nature of the protocol provides a great advantage by omitting the tedious step of manual landmark indication on the biological structure of interest.

Indexed as

AdolescentAdultAlgorithmsAnthropometryFaceFacial AsymmetryFemaleHumansImaging, Three-DimensionalMaleYoung Adult

Identifiers

PMID30586353
PMCPMC6306226
OpenAlexW2905944778

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.