ArticleScience advances2018
Direct brain recordings reveal prefrontal cortex dynamics of memory development.
Article in Science advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Single-Neuron Recordings Research in Children: Ethical Considerations, Feasibility, Technical Aspects, and Scientific Opportunities.Pediatric neurosurgery · 2026Review
- The development of aperiodic neural activity in the human brain.Nature human behaviour · 2025Article
- Episodic memory involves transient and sparse connectivity aligned to both internal and external events.PLoS biology · 2025Article
- Dynamic Causal Tractography Analysis of Auditory Descriptive Naming: An Intracranial Study of 106 Patients.NeuroImage · 2025Article
- Article
- High frequency broadband activity detected noninvasively in infants distinguishes wake from sleep states.bioRxiv : the preprint server for biology · 2025Article
- Visualization of functional and effective connectivity underlying auditory descriptive naming.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025Article
- Reinstatement and transformation of memory traces for recognition.Science advances · 2025Article
- Cortical and white matter substrates supporting visuospatial working memory.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024Article
- Neurophysiological mechanisms of cognition in the developing brain: Insights from intracranial EEG studies.Developmental cognitive neuroscience · 2023Review
- Associations between mother's depressive symptoms during pregnancy and newborn's brain functional connectivity.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- A rapid theta network mechanism for flexible information encoding.Nature communications · 2023Article
- Verbal memory and executive components of recall in adolescent binge drinkers.Frontiers in psychology · 2023Article
- Reward Enhances Memory via Age-Varying Online and Offline Neural Mechanisms across Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Dissociable oscillatory theta signatures of memory formation in the developing brain.Current biology : CB · 2022Article
- Interactions between the hippocampus and fronto-parietal regions during memory encoding in early childhood.Hippocampus · 2022Article
- Task-specific modulation of PFC activity for matching-rule governed decision-making.Brain structure & function · 2021Article
- Direct brain recordings reveal occipital cortex involvement in memory development.Neuropsychologia · 2020Article
- Insights into human cognition from intracranial EEG: A review of audition, memory, internal cognition, and causality.Journal of neural engineering · 2020Review
- Frontoparietal connectivity correlates with working memory performance in multiple sclerosis.Scientific reports · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
Abstract
Prevailing theories link prefrontal cortex (PFC) maturation to the development of declarative memory. However, the precise spatiotemporal correlates of memory formation in the developing brain are not known. We provide rare intracranial evidence that the spatiotemporal propagation of frontal activity supports memory formation in children. Seventeen subjects (6.2 to 19.4 years) studied visual scenes in preparation for a recognition memory test while undergoing direct cortical monitoring. Earlier PFC activity predicted greater accuracy, and subsecond deviations in activity flow between subregions predicted memory formation. Activity flow between inferior and precentral sites was refined during adolescence, partially explaining gains in memory. In contrast, middle frontal activity predicted memory independent of age. These findings show with subsecond temporal precision that the developing PFC links scene perception and memory formation and underscore the role of the PFC in supporting memory development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.