Evidence map›Paper›PMID 30585270›Full record

ArticleInternational journal of biological sciences2018

TRIM59 Is a Novel Marker of Poor Prognosis and Promotes Malignant Progression of Ovarian Cancer by Inducing Annexin A2 Expression.

You Wang, Zhicheng Zhou, Xinran Wang, Xuping Zhang, Yansu Chen, Jin Bai, Wen Di

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Annexin Animal Models-From Fundamental Principles to Translational Research.International journal of molecular sciences · 2021
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. [Expression of TRIM59 in Non-small Cell Lung Cancer and Its Correlation with Prognosis].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2020
    Article
  19. Review
  20. TRIM proteins in neuroblastoma.Bioscience reports · 2019
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

You WangDepartment of Obstetrics and Gynecology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200001, China.
Zhicheng ZhouDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
Xinran WangDepartment of Obstetrics and Gynecology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200001, China.
Xuping ZhangCancer Institute, Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China.
Yansu ChenCancer Institute, Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China.
Jin BaiCancer Institute, Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China.
Wen DiDepartment of Obstetrics and Gynecology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200001, China.
Xuzhou Medical College · CNRenji Hospital · CNBaylor College of Medicine · USShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer is the fifth common cause of death in woman worldwide. The tripartite motif-containing (TRIM) proteins consist of more than 70 known protein members. Studies have showed that TRIM proteins are involved in cancer and play important roles in cancer cell proliferation, migration, adhesion and metastasis. Recent studies have indicated that TRIM59, as a putative ubiquitin ligase, is up-regulated in some cancers and associated with poor prognosis of gastric cancer. However, the exact roles of TRIM59 in ovarian cancer are still unknown. In this study, we found that TRIM59 expression was increased and positively associated with histological grades (

Indexed as

AnimalsAnnexin A2Cell Line, TumorCell ProliferationFemaleGene Expression Regulation, NeoplasticHumansImmunohistochemistryImmunoprecipitationIntracellular Signaling Peptides and ProteinsMembrane ProteinsMetalloproteinsMice, Inbred BALB CMice, NudeMiddle AgedOvarian NeoplasmsAnnexin A2Intracellular Signaling Peptides and ProteinsMembrane ProteinsMetalloproteinsTRIM59 protein, humanTripartite Motif ProteinsAnnexin A2MetastasisOvarian cancerTissue microarrayTRIMP59

Identifiers

PMID30585270
PMCPMC6299375
OpenAlexW2898644468

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.