Evidence map›Paper›PMID 30585264›Full record

ReviewInternational journal of biological sciences2018

The roles of Wnt/β-catenin signaling pathway related lncRNAs in cancer.

Xiao-Yi Hu, Ping-Fu Hou, Teng-Teng Li, Hao-Yu Quan, Min-Le Li, Tian Lin, Jin-Jin Liu, Jin Bai, Jun-Nian Zheng

Abstract readReview
In one paragraph

Review in International journal of biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiao-Yi HuCancer Institute, Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China.
Ping-Fu HouCancer Institute, Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China.
Teng-Teng LiDepartment of Gastrointestinal Surgery, the Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China.
Hao-Yu QuanCancer Institute, Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China.
Min-Le LiCancer Institute, Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China.
Tian LinCancer Institute, Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China.
Jin-Jin LiuCancer Institute, Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China.
Jin BaiCancer Institute, Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China.
Jun-Nian ZhengCancer Institute, Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long noncoding RNAs (lncRNAs), with length of more than 200 nucleotides, are not translated into proteins but involved in multiple diverse diseases, especially tumorigenesis. The dysregulation of lncRNAs greatly contributes to the progression of various tumors through specific signaling pathways, including Wnt/β-catenin signaling pathway, which is associated with malignant features of tumors. The interactions between lncRNAs, which have specific expression characteristics in diverse cancer tissues, and Wnt/β-catenin signaling pathway, exhibit potential as novel biomarkers and therapeutic targets. In this review, we aim to present research findings on the roles of Wnt pathway-related lncRNAs and their effects on Wnt/β-catenin signaling to regulate tumorigenesis in different cancer types. Results may be used as basis to develop or improve strategies for treatment of different carcinomas.

Indexed as

AnimalsCell MovementCell ProliferationGene Expression Regulation, NeoplasticHumansRNA, Long NoncodingWnt Signaling PathwayRNA, Long Noncodingcancerlong non-coding RNAWnt/β-catenin signaling pathway

Identifiers

PMID30585264
PMCPMC6299370

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.