Evidence map›Paper›PMID 30585204›Full record

ArticleInternational journal of environmental research and public health2018

Relationship between Serum Omega-3 Fatty Acid and Asthma Endpoints.

Shahieda Adams, Andreas L Lopata, Cornelius M Smuts, Roslynn Baatjies, Mohamed F Jeebhay

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
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  5. Review
  6. Per and poly-fluoroalkyl substances and respiratory health in an Inuit community.Environmental health : a global access science source · 2024
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  9. Article
  10. Evaluating the Effect of Eicosapentaenoic Acid in Children With Atopic Dermatitis: A Randomized Triple-Blind Clinical Trial.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2023
    Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. IgE-Mediated Fish Allergy in Children.Medicina (Kaunas, Lithuania) · 2021
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Shahieda AdamsOccupational Medicine Division and Centre for Environmental and Occupational Health Research, School of Public Health and Family Medicine, University of Cape Town, Observatory, 7925 Cape Town, South Africa. shahieda.adams@uct.ac.za.
Andreas L LopataMolecular Allergy Research Laboratory, School of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Douglas, QLD 4814, Australia. andreas.lopata@jcu.edu.au.
Cornelius M SmutsCentre of Excellence for Nutrition, North-West University, Potchefstroom 2520, South Africa. Marius.Smuts@nwu.ac.za.
Roslynn BaatjiesOccupational Medicine Division and Centre for Environmental and Occupational Health Research, School of Public Health and Family Medicine, University of Cape Town, Observatory, 7925 Cape Town, South Africa. roslynn.baatjies@uct.ac.za.
Mohamed F JeebhayOccupational Medicine Division and Centre for Environmental and Occupational Health Research, School of Public Health and Family Medicine, University of Cape Town, Observatory, 7925 Cape Town, South Africa. Mohamed.Jeebhay@uct.ac.za.ORCID 0000-0001-6656-9193
University of Cape Town · ZAJames Cook University · AUNorth-West University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have highlighted the potential protective role of omega-3 polyunsaturated fatty acids (n-3 PUFA) in asthma. This study aimed at determining the association between seafood intake, serum PUFA composition and clinical endpoints of asthma in adults. A cross-sectional study of 642 subjects used the European Committee Respiratory Health Survey (ECRHS) questionnaire, skin prick tests, spirometry and methacholine challenge tests following ATS guidelines. Sera was analysed for n-3 and n-6 PUFA composition. Subjects had a mean age of 34 years, were largely female (65%) and 51% were current smokers. While 99% reported fish consumption, rock lobster, mussels, squid and abalone were also consumed less frequently. The prevalence of asthma symptoms was 11%, current asthma (ECRHS definition) was 8% and non-specific bronchial hyperresponsiveness (NSBH) was much higher (26%) In adjusted models the n-3 PUFAs 20:5 (EPA) and 22:5 (DPA) were significantly associated with a decreased risk of having NSBH. Total n-3 PUFA composition was associated with decreased NSBH risk (OR = 0.92), while high n-6 PUFA composition was associated with an increased risk (OR = 1.14).

Indexed as

AdultAsthmaBronchial HyperreactivityCross-Sectional StudiesFatty Acids, Omega-3FemaleFood HandlingHumansMaleMiddle AgedOccupational ExposurePrevalenceSeafoodSkin TestsSouth AfricaSpirometryFatty Acids, Omega-3asthma clinical endpointsnon-specific bronchial hyperresponsivenessomega-3 fatty acidsomega-6 fatty acidspolyunsaturated fatty acids

Identifiers

PMID30585204
PMCPMC6338947
OpenAlexW2905759281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.