ReviewThe Journal of pathology2019
Neutrophil trafficking to lymphoid tissues: physiological and pathological implications.
Review in The Journal of pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- New Insights Into the Role of Neutrophils in Lymphoma.Cancer medicine · 2026Review
- Dynamic changes and roles of LYVE-1 during lipopolysaccharide-induced ALI/ARDS in mice.BBA advances · 2026Article
- Neutrophils in Rheumatoid Arthritis Synovium: Implications on Disease Activity and Inflammation State.Journal of inflammation research · 2025Article
- The Role of Neutrophil Extracellular Traps in the Outcome of Malignant Epitheliomas: Significance of CA215 Involvement.Diagnostics (Basel, Switzerland) · 2024Review
- Nuclear segmentation facilitates neutrophil migration.Journal of cell science · 2023Article
- Review
- The Olfactory Organ Is a Unique Site for Neutrophils in the Brain.Frontiers in immunology · 2022Article
- Neutrophils in secondary lymphoid organs.Immunology · 2021Review
- Neutrophil and Eosinophil Extracellular Traps in Hodgkin Lymphoma.HemaSphere · 2021Article
- Review
- Expansion of CD10eLife · 2021Article
- Review
- Specialized Pro-Resolving Mediators and the Lymphatic System.International journal of molecular sciences · 2021Review
- The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation.Nature communications · 2021Article
- Endothelial Focal Adhesions Are Functional Obstacles for Leukocytes During Basolateral Crawling.Frontiers in immunology · 2021Article
- Effect of VEGFC on lymph flow and inflammation-induced alveolar bone loss.The Journal of pathology · 2020Article
- The Secretive Life of Neutrophils Revealed by Intravital Microscopy.Frontiers in cell and developmental biology · 2020Review
- Plasticity in Pro- and Anti-tumor Activity of Neutrophils: Shifting the Balance.Frontiers in immunology · 2020Review
- Extracellular RNA as a Versatile DAMP and Alarm Signal That Influences Leukocyte Recruitment in Inflammation and Infection.Frontiers in cell and developmental biology · 2020Review
- Host⁻Microbe Interactions and Gut Health in Poultry-Focus on Innate Responses.Microorganisms · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Recent advances have provided evidence for the involvement of neutrophils in both innate and adaptive immunity, robustly challenging the old dogma that neutrophils are short-lived prototypical innate immune cells solely involved in acute responses to microbes and exerting collateral tissue damage. There is now ample evidence showing that neutrophils can migrate into different compartments of the lymphoid system where they contribute to the orchestration of the activation and/or suppression of lymphocyte effector functions in homeostasis and during chronic inflammation, such as autoimmune disorders and cancer. In support of this notion, neutrophils can generate a wide range of cytokines and other mediators capable of regulating the survival, proliferation and functions of both T and B cells. In addition, neutrophils can directly engage with lymphocytes and promote antigen presentation. Furthermore, there is emerging evidence of the existence of distinct and diverse neutrophil phenotypes with immunomodulatory functions that characterise different pathological conditions, including chronic and autoimmune inflammatory conditions. The aim of this review is to discuss the mechanisms implicated in neutrophil trafficking into the lymphoid system and to provide an overview of the immuno-regulatory functions of neutrophils in health and disease in the context of adaptive immunity. Copyright © 2018 The Authors. The Journal of Pathology published by John Wiley & Sons Ltd on behalf of Pathological Society of Great Britain and Ireland.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.