Evidence map›Paper›PMID 30584620›Full record

ArticleJournal of veterinary research2018

Evaluation of Intestinal Damage Biomarkers in Calves with Atresia Coli.

Ramazan Yildiz, Mahmut Ok, Merve Ider, Ugur Aydogdu, Amir Naseri, Kurtulus Parlak, Erdem Gulersoy

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In one paragraph

Article in Journal of veterinary research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Ramazan YildizDepartment of Internal Medicine, Faculty of Veterinary Medicine, Mehmet Akif Ersoy University, 15030, Burdur, Turkey.
Mahmut OkDepartment of Internal Medicine, 42003, Konya, Turkey.
Merve IderDepartment of Internal Medicine, 42003, Konya, Turkey.
Ugur AydogduDepartment of Internal Medicine, Faculty of Veterinary Medicine, Balikesir University, 10145, Balikesir, Turkey.
Amir NaseriDepartment of Internal Medicine, 42003, Konya, Turkey.
Kurtulus ParlakDepartment of Surgery, Faculty of Veterinary Medicine, Selcuk University, 42003, Konya, Turkey.
Erdem GulersoyDepartment of Internal Medicine, 42003, Konya, Turkey.
Konya Food and Agriculture University · TRBalıkesir University · TRBurdur Mehmet Akif Ersoy Üniversitesi · TRSelçuk University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIntestinal obstruction such as atresia coli causes pathophysiological changes in gastrointestinal tissue due to the rise of intra-abdominal pressure. The aim of this study is to determine the intestinal damage with intestinal biomarkers in calves with atresia coli. MATERIAL AND

methodsThe study was conducted on 40 Holstein calves diagnosed with atresia coli with mild to moderate abdominal distention and 10 healthy Holstein calves which served as the control. Blood samples were collected from all calves, and then serum concentrations of intestinal biomarkers were estimated, namely intestinal fatty acid binding protein (IFABP), liver fatty acid binding protein (LFABP), trefoil factor 3 (TFF3), and intestinal alkaline phosphatase (IAP), using commercially available specific bovine ELISA kits. An automatic blood gas analyser was employed for determining the lactate concentration.

resultsThe concentrations of serum LFABP (P < 0.01), IFABP, TFF3, IAP, and blood lactate (P < 0.001) were significantly higher in calves with atresia coli than in healthy calves.

conclusionThe calves affected with atresia coli exhibited severe intestinal damage, and IFABP, LFABP, and TFF3 have significant diagnostic importance and play a useful role in determining the intestinal damage due to intestinal obstruction. High levels of IAP and lactate may serve as a signal for the development of intestinal injury.

Indexed as

atresia colicalvesIFABPLFABPTFF3

Identifiers

PMID30584620
PMCPMC6295999
OpenAlexW2993062647

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.