Evidence map›Paper›PMID 30584581›Full record

ArticleChronic obstructive pulmonary diseases (Miami, Fla.)2018

Race and Gender Disparities are Evident in COPD Underdiagnoses Across all Severities of Measured Airflow Obstruction.

A James Mamary, Jeffery I Stewart, Gregory L Kinney, John E Hokanson, Kartik Shenoy, Mark T Dransfield, Marilyn G Foreman, Gwendolyn B Vance, Gerard J Criner, COPDGene® Investigators

Open access · diamondAbstract read
In one paragraph

Article in Chronic obstructive pulmonary diseases (Miami, Fla.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Race-Based Pulmonary Function Testing Correction in COPD Inhaler Therapy Trials: A Systematic Review.International journal of chronic obstructive pulmonary disease · 2024
    Pooled it
  3. Article
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  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Diagnostic Inaccuracies in COPD: Misdiagnosis, Race and Gender Disparities.International journal of chronic obstructive pulmonary disease · 2025
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Testing Alpha-1 Antitrypsin Deficiency in Black Populations.Advances in respiratory medicine · 2023
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

A James MamaryDepartment of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University Health System, Philadelphia, Pennsylvania.
Jeffery I StewartDepartment of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University Health System, Philadelphia, Pennsylvania.
Gregory L KinneyDepartment of Epidemiology, Colorado School of Public Health, Anschutz Medical Campus, University of Colorado, Aurora.
John E HokansonDepartment of Epidemiology, Colorado School of Public Health, Anschutz Medical Campus, University of Colorado, Aurora.
Kartik ShenoyDepartment of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University Health System, Philadelphia, Pennsylvania.
Mark T DransfieldDivision of Pulmonary, Allergy and Critical Care Medicine, University of Alabama, Birmingham.
Marilyn G ForemanDivision of Pulmonary and Critical Care Medicine, Morehouse School of Medicine, Atlanta, Georgia.
Gwendolyn B VanceDepartment of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University Health System, Philadelphia, Pennsylvania.
Gerard J CrinerDepartment of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University Health System, Philadelphia, Pennsylvania.
COPDGene® Investigators
University Health System · USTemple University Health System · USColorado School of Public Health · USMorehouse School of Medicine · USUniversity of Alabama at Birmingham · USUniversity of Colorado Anschutz Medical Campus · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COPD Genetic Epidemiology (COPDGene®) study provides a rich cross-sectional dataset of patients with substantial tobacco smoke exposure, varied by race, gender, chronic obstructive pulmonary disease (COPD) diagnosis, and disease. We aimed to determine the influence of race, gender and Global initiative for chronic Obstructive Lung Disease (GOLD) stage on prevalence of prior COPD diagnosis at COPDGene® enrollment. Data from the complete phase 1 cohort of 10,192 participants were analyzed. Participants were non-Hispanic white and African-American, ≥45 years of age with a minimum of 10 pack years of cigarette smoking. Characterization upon enrollment included spirometry, demographics and history of COPD diagnosis determined by questionnaire. We evaluated the effects of race and gender on the likelihood of prior diagnosis of COPD and the interaction of race and GOLD stage, and gender and GOLD stage, as determined at study enrollment, on likelihood of prior diagnosis of COPD. We evaluated the 3-way interaction of race, gender and GOLD stage on prior diagnosis. African-Americans had higher odds of not having a prior COPD diagnosis at all GOLD stages of airflow obstruction versus non-Hispanic whites (

Indexed as

asthmadiagnosisepidemiologysmokersspirometrytobacco

Identifiers

PMID30584581
PMCPMC6296789
OpenAlexW2831995786

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.