Evidence map›Paper›PMID 30584542›Full record

ReviewJournal of immunology research2018

Cutting Edge: Biomarkers for Chronic Spontaneous Urticaria.

Marco Folci, Enrico Heffler, Giorgio W Canonica, Raffaello Furlan, Enrico Brunetta

Open access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 48 citations in OpenAlex.

  1. The Added-on ofIranian journal of medical sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Marco FolciDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.ORCID 0000-0001-5618-2876
Enrico HefflerDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.ORCID 0000-0002-0492-5663
Giorgio W CanonicaDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Raffaello FurlanDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Enrico BrunettaDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.ORCID 0000-0002-0676-1228
Humanitas University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic spontaneous urticaria (CSU) is defined by the appearance of wheals and a variable presence of angioedema which persists for at least 6 weeks. It represents the most common subtype of chronic urticaria and is gaining importance in civil society because of its association with impaired quality of life. Moreover, CSU has a growing impact on national health systems representing a great burden due to its variable rate of response to the approved therapies. In this scenario, the identification of clinical and molecular biomarkers is of pivotal importance. Some groups are trying to detect molecules which would be able to help clinicians in reaching a proper diagnosis; additionally, the opportunity to describe disease severity which leads to cluster patients in different groups could fill the gap in the numerous unmet clinical needs. Several biomarkers are currently being studied with the purpose to predict the response to a defined therapy; unfortunately, none of them are ready to be translated from bench to bedside.

Indexed as

AnimalsAnti-Allergic AgentsBasophilsBiomarkersBiomarkers, PharmacologicalChronic DiseaseCytokinesFibrin Fibrinogen Degradation ProductsHumansOmalizumabPhenotypeUrticariaAnti-Allergic AgentsBiomarkersBiomarkers, PharmacologicalCytokinesFibrin Fibrinogen Degradation Productsfibrin fragment DOmalizumab

Identifiers

PMID30584542
PMCPMC6280255
OpenAlexW2901619635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.