Evidence map›Paper›PMID 30584475›Full record

ArticleJournal of obesity2018

A Strong Graded Relationship between Level of Obesity and COPD: Findings from a National Population-Based Study of Lifelong Nonsmokers.

Esme Fuller-Thomson, Kaitlyn E N Howden, Lilia R Fuller-Thomson, Senyo Agbeyaka

Open access · goldAbstract read
In one paragraph

Article in Journal of obesity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Review
  9. Weight change across adulthood in relation to the risk of COPD.Environmental health and preventive medicine · 2025
    Article
  10. Article
  11. Article
  12. Adverse childhood experiences and adult disease: Examining mediating pathways in the Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Healthy Sleep Every Day Keeps the Doctor Away.International journal of environmental research and public health · 2022
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Esme Fuller-ThomsonFactor-Inwentash Faculty of Social Work and Department of Family and Community Medicine, Director, Institute of Life Course & Aging, University of Toronto, 246 Bloor Street West, Toronto, Ontario, Canada M5S 1A1.ORCID 0000-0002-9705-6216
Kaitlyn E N HowdenMcMaster University, Michael G. DeGroote School of Medicine, 1280 Main Street West, Michael DeGroote Centre for Learning and Discovery, Hamilton, Canada ON L8S 4K1.ORCID 0000-0001-8422-5087
Lilia R Fuller-ThomsonInstitute of Life Course & Aging, University of Toronto, 246 Bloor St. W., Room 238, Toronto, Ontario, Canada M5S 1V4.ORCID 0000-0001-5888-429X
Senyo AgbeyakaFactor-Inwentash Faculty of Social Work and University Health Network, 246 Bloor St. W., Room 238, Toronto, Ontario, Canada M5S 1V4.ORCID 0000-0003-3528-7753
University of Toronto · CADiscovery Centre · CAUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Factors associated with chronic obstructive pulmonary disease (COPD) among never-smokers have received little research attention. One potential risk factor for COPD is obesity, which is of particular importance in light of the global obesity epidemic. The objective of this study was to investigate the association between COPD and levels of obesity in a nationally representative sample of non-Hispanic white never-smokers. Data were drawn from the 2012 Center for Disease Control's Behavioral Risk Factor Surveillance System (BRFSS). Pearson's chi-square tests and logistic regression analyses were conducted in a large nationally representative sample of non-Hispanic white respondents aged 50 and over (76,004 women; 37,618 men) who reported that they had never smoked. A dose-response relationship was observed for both men and women: the prevalence of COPD increased from 2.5% in men and 3.5% in women who were of a healthy weight (BMI < 25) to 7.6% in men and 13.4% in women who had a BMI of 40 or higher. Even after adjusting for 7 potential confounds (e.g., age, education, and income), the odds of COPD were 3.21 higher for men (95% CI = 2.46, 4.20) and 4.00 higher for women with class III obesity (95% CI = 3.52, 4.55) in comparison with those of healthy weight. Regular screening for COPD is warranted in never-smoking obese patients who are aged 50 and over. Future research is needed to investigate plausible mechanisms for this association, including (1) the role of chronic inflammation associated with obesity and (2) the impact of central obesity on respiratory system mechanics.

Indexed as

Non-SmokersAgedAged, 80 and overBody Mass IndexFemaleHumansMaleMiddle AgedObesityPrevalencePulmonary Disease, Chronic ObstructiveRisk FactorsSocial ClassUnited States

Identifiers

PMID30584475
PMCPMC6280223
OpenAlexW2901759522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.