Evidence map›Paper›PMID 30584465›Full record

ArticleOxidative medicine and cellular longevity2018

Interleukin-4 Boosts Insulin-Induced Energy Deposits by Enhancing Glucose Uptake and Lipogenesis in Hepatocytes.

Ching-Ping Yang, Ming-Yuh Shiau, Yi-Ren Lai, Kuo-Ting Ho, Chiao-Wan Hsiao, Chun-Jung Chen, Yu-Li Lo, Yih-Hsin Chang

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Ching-Ping YangDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Ming-Yuh ShiauDepartment of Nursing, College of Nursing, Hungkuang University, Taichung, Taiwan.
Yi-Ren LaiDepartment of Biotechnology and Laboratory Science in Medicine, National Yang-Ming University, Taipei, Taiwan.
Kuo-Ting HoDepartment of Biotechnology and Laboratory Science in Medicine, National Yang-Ming University, Taipei, Taiwan.ORCID 0000-0001-7224-1338
Chiao-Wan HsiaoDepartment of Biotechnology and Laboratory Science in Medicine, National Yang-Ming University, Taipei, Taiwan.
Chun-Jung ChenDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Yu-Li LoDepartment and Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan.
Yih-Hsin ChangDepartment of Biotechnology and Laboratory Science in Medicine, National Yang-Ming University, Taipei, Taiwan.ORCID 0000-0002-8262-6589
National Yang Ming Chiao Tung University · TWTaichung Veterans General Hospital · TWHungkuang University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 diabetes mellitus (T2DM), with dysregulated hepatic gluconeogenesis as the major cause of fasting hyperglycemia, is closely associated with chronic inflammation. We previously demonstrated interleukin-4 (IL-4) improves insulin sensitivity and glucose tolerance while reducing lipid deposits. The present study examined the

Indexed as

AnimalsBlotting, WesternDiabetes Mellitus, Type 2GlucoseHepatocytesHep G2 CellsHumansInsulinInterleukin-4Lipid MetabolismMaleMice, Inbred C57BLSignal TransductionTriglyceridesGlucoseInsulinInterleukin-4Triglycerides

Identifiers

PMID30584465
PMCPMC6280305
OpenAlexW2901872961

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.