ReviewInternational journal of endocrinology and metabolism2018
Outcomes of a Longitudinal Population-based Cohort Study and Pragmatic Community Trial: Findings from 20 Years of the Tehran Lipid and Glucose Study.
Review in International journal of endocrinology and metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed.
- Age-dependent association of thyroid peroxidase antibodies with incident cardiovascular disease events: Insights from a longitudinal cohort study.Journal of translational autoimmunity · 2026Article
- Clinical value of the new obesity definition for cardiovascular events in a Middle Eastern population: the TLGS.American journal of preventive cardiology · 2026Article
- Nonlinear association between glycemic markers and incident cardio‑renal‑metabolic multimorbidity: two decades of follow‑up in the Tehran Lipid and Glucose Study.American journal of preventive cardiology · 2025Article
- Evaluating the association between TSH and FT4 levels and the incidence of metabolic syndrome: insights from the Tehran thyroid study using joint modeling.Scientific reports · 2025Article
- Association of the triglyceride-glucose index and its combination with obesity indices with cardio-renal-metabolic multimorbidity: two decades of follow-up in the Tehran Lipid and Glucose Study.Cardiovascular diabetology · 2025Article
- Different Metabolic Phenotypes of Obesity and 2 Decades Risk of Cardio-Renal-Metabolic Multimorbidity: Tehran Lipid and Glucose Study.Journal of the American Heart Association · 2025Article
- Association of Lipid Profile With Cardiovascular Diseases and All-Cause Death: A 2-Decade Follow-Up of the Tehran Lipid and Glucose Study.Journal of the American Heart Association · 2025Article
- Prolactin levels and chronic kidney disease and the subsequent risk of cardiovascular events: A long term population based cohort study.Scientific reports · 2025Article
- Evaluation of the effectiveness of the Iran-package of essential non-communicable disease (IraPEN) program in reducing cardiovascular disease risk in pilot areas.BMC public health · 2025Article
- Progression to diabetes and regression to normoglycemia in pre-diabetic subjects: results from a pragmatic community trial in a middle-income country.Journal of diabetes and metabolic disorders · 2024Article
- Association between metabolic score for insulin resistance and clinical outcomes: insights from the Tehran lipid and glucose study.Nutrition & metabolism · 2024Article
- The impact of obesity on different glucose tolerance status with incident cardiovascular disease and mortality events over 15 years of follow-up: a pooled cohort analysis.Diabetology & metabolic syndrome · 2024Article
- Article
- Association between changes in thyroid hormones and incident type 2 diabetes using joint models of longitudinal and time-to-event data: more than a decade follow up in the Tehran thyroid study.Frontiers in endocrinology · 2024Article
- Adiposity trajectories and cardiovascular disease risk in women: a population-based cohort study with a focus on menopausal status.Frontiers in endocrinology · 2024Article
- Sex differences in risk factors for coronary heart disease events: a prospective cohort study in Iran.Scientific reports · 2023Article
- Factors associated with smoking intensity among adult smokers: findings from the longitudinal cohort of the Tehran lipid and glucose study.BMC public health · 2023Article
- Association between estimated glomerular filtration rate slope and cardiovascular disease among individuals with and without diabetes: a prospective cohort study.Cardiovascular diabetology · 2023Article
- The impact of general and central obesity for all-cause hospitalization among Iranian adults: a 20 year follow-up-results from the TLGS cohort.BMC public health · 2023Article
- Changes in Fasting plasma glucose status and risk of mortality events in individuals without diabetes over two decades of Follow-up: a pooled cohort analysis.Cardiovascular diabetology · 2022Article
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Authors and funding
9 authors.
Funding
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Abstract
contextThe Tehran lipid and glucose study (TLGS) is one of the oldest population-based longitudinal cohort studies, providing knowledge about the incidence and risk factors of some non-communicable diseases (NCDs) in West Asia which hitherto was relatively scarce. We reviewed the methods and results related to the outcome measurements of this study. EVIDENCE ACQUISITION: We reviewed all the TLGS papers which reported the incidence of NCDs.
resultsThe TLGS was initiated in 1999 - 2001 on a population in district no. 13 of Tehran with the same age distribution of the overall Tehran population and with a middle socioeconomic status. Totally, 15005 individuals, aged ≥ 3 years, participated in the first examination; reexaminations were conducted in a triennial manner and 3550 individuals were added in the second examination. All participants were also followed up annually and asked about any medical event leading to hospitalization or death. A part of participants was assigned to an educational program for lifestyle modification. High incidence of cardiovascular disease (CVD), premature CVD, diabetes and hypertension (around 19, 6, 10 and 31 in men and 11, 5, 11 and 29 in women per 1000 person-year, respectively) besides the high incidence of pre-diabetes and pre-hypertension (around 46 and 76 in men and 37 and 49 in women per 1000 person-year, respectively) showed a worrying situation. Fortunately, the results of the community interventions were promising with around 20% reduction in the risk of metabolic syndrome up to six years.
conclusionsThese precise detections of different outcomes in the TLGS provided valuable evidences for prediction and prevention of NCDs in Iran with some novelties in the middle-income countries in the world. The Tehran thyroid study (TTS) and the Tehran cardiometabolic genetic study (TCGS), conducted in the framework of the TLGS, are among few studies aiming to determine the natural course of thyroid function and to identify patterns of genetic polymorphisms related to cardiometabolic outcomes, respectively.
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