ArticleNeuropsychiatric disease and treatment2018
Altered functional connectivity of primary visual cortex in late blindness.
Article in Neuropsychiatric disease and treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Characteristics of striatal changes in diabetic retinopathy and type 2 diabetes: a resting-state functional magnetic resonance imaging study.Frontiers in human neuroscience · 2026Article
- Gray matter abnormalities in sight deprivation and sight restoration.Brain structure & function · 2025Article
- Altered spontaneous brain activity in children with deprivation amblyopia: a resting-state functional magnetic resonance imaging study.European journal of medical research · 2025Article
- Brain structural changes in diabetic retinopathy patients: a combined voxel-based morphometry and surface-based morphometry study.Brain imaging and behavior · 2024Article
- Study of vision-related resting-state activity in suprasellar tumor patients with postoperative visual damage.Brain and behavior · 2024Article
- Continuous and intermittent theta burst stimulation of primary visual cortex do not modulate resting state functional connectivity: A sham-controlled multi-echo fMRI study.Brain and behavior · 2023Article
- Exploration of static functional connectivity and dynamic functional connectivity alterations in the primary visual cortex among patients with high myopiaFrontiers in neuroscience · 2023Article
- Altered dynamic functional connectivity in the primary visual cortex in patients with primary angle-closure glaucoma.Frontiers in neuroscience · 2023Article
- Altered functional connectivity of the right caudate nucleus in chronic migraine: a resting-state fMRI study.The journal of headache and pain · 2022Article
- Association of Inner Retinal Thickness with Prevalent Dementia and Brain Atrophy in a General Older Population: The Hisayama Study.Ophthalmology science · 2022Article
- Resting-State Neuronal Activity and Functional Connectivity Changes in the Visual Cortex after High Altitude Exposure: A Longitudinal Study.Brain sciences · 2022Article
- Sight restoration reverses blindness-induced cross-modal functional connectivity changes between the visual and somatosensory cortex at rest.Frontiers in neuroscience · 2022Article
- Altered Spontaneous Brain Activity and Network Property in Patients With Congenital Monocular Blindness.Frontiers in neurology · 2022Article
- Aberrant Amplitude of Low-Frequency Fluctuation and Degree Centrality within the Default Mode Network in Patients with Vascular Mild Cognitive Impairment.Brain sciences · 2021Article
- Occipital cortex is modulated by transsaccadic changes in spatial frequency: an fMRI study.Scientific reports · 2021Article
- Brain-Machine Interfaces to Assist the Blind.Frontiers in human neuroscience · 2021Review
- Altered Functional Connectivity Strength of Primary Visual Cortex in Subjects with Diabetic Retinopathy.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- Altered Functional Connectivity of the Primary Visual Cortex in Patients With Iridocyclitis and Assessment of Its Predictive Value Using Machine Learning.Frontiers in immunology · 2021Article
- Reduced Functional Connectivity in Children With Congenital Cataracts Using Resting-State Electroencephalography Measurement.Frontiers in neuroscience · 2021Article
- Altered Intrinsic Functional Connectivity of the Primary Visual Cortex in Patients with Corneal Ulcer: A Resting-State fMRI Study.Neuropsychiatric disease and treatment · 2020Article
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6 authors.
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Abstract
backgroundPrevious studies demonstrated that early blindness is associated with abnormal intrinsic functional connectivity (FC) between the primary visual cortex (V1) and other sensory areas. However, the V1 pattern of spontaneous neural activity occurring in late blindness (LB) remains unknown. The purpose of this study was to investigate the intrinsic FC patterns of V1 in LB. MATERIALS AND
methodsThirty LB individuals (18 males and 12 females; mean age: 38.76±14.43 years) and 30 sighted controls (SCs) individuals (18 males and 12 females; mean age: 38.67±13.85 years) closely matched for age, sex, and education, underwent resting-state magnetic resonance imaging scans. Region of interest analysis was performed to extract the correlation coefficient matrix among each pair of Brodmann area (BA) 17 and FC between V1 and vision-related subcortical nuclei.
resultsCompared with SCs, LB individuals showed a decreased FC between the left V1 and the bilateral cuneus (CUN)/lingual gyrus (LGG)/calcarine (CAL) (BA 18/19/30) and left precentral gyrus (PreCG) and the postcentral gyrus (PostCG) (BA 2/3/4). Also, LB individuals showed a decreased FC between the right V1 and the bilateral CUN/LGG/CAL (BA 18/19/30) and the left PreCG and PostCG (BA 2/3/4/6) (voxel-level:
conclusionOur results highlighted that LB induces a decreased FC between V1 and higher visual areas, motor cortices, and somatosensory cortices at rest. This might indicate that LB humans could present with impaired top-down modulations, visual imagery, and vision-motor function.
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