Evidence map›Paper›PMID 30584253›Full record

ArticleScientific reports2018

Whole exome sequencing for the identification of CYP3A7 variants associated with tacrolimus concentrations in kidney transplant patients.

Minji Sohn, Myeong Gyu Kim, Nayoung Han, In-Wha Kim, Jungsoo Gim, Sang-Il Min, Eun Young Song, Yon Su Kim, Hun Soon Jung, Young Kee Shin and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Massively parallel reporter assays forbioRxiv : the preprint server for biology · 2026
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  4. Synergistic Effect of Cytochrome P450 Family 3 Subfamily A Member 5 (ACS pharmacology & translational science · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Minji SohnCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
Myeong Gyu KimCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
Nayoung HanCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
In-Wha KimCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
Jungsoo GimDepartment of Biomedical Science, Chosun University, Gwangju, Republic of Korea.
Sang-Il MinDepartment of Surgery, Seoul National University Hospital, Seoul, Republic of Korea.
Eun Young SongDepartment of Laboratory Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Yon Su KimKidney Research Institute and Department of Medical Science, Seoul National University College of Medicine, Seoul, Republic of Korea.
Hun Soon JungR&D center, ABION, Inc., Seoul, Republic of Korea.
Young Kee ShinCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
Jongwon HaDepartment of Surgery, Seoul National University Hospital, Seoul, Republic of Korea. jwhamd@snu.ac.kr.
Jung Mi OhCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea. jmoh@snu.ac.kr.ORCID http://orcid.org/0000-0002-1836-1707
Seoul National University · KRSeoul National University Hospital · KRChosun University · KR

Funding

National Research Foundation of Korea (NRF) NRF-2014M3C1B3064644
6 · The paper itself

Abstract

The purpose of this study was to identify genotypes associated with dose-adjusted tacrolimus trough concentrations (C

Indexed as

Kidney TransplantationPharmacogenomic VariantsPolymorphism, Single NucleotideAdultCytochrome P-450 CYP3AExome SequencingFemaleHumansImmunosuppressive AgentsMaleMiddle AgedTacrolimusTransplant RecipientsCYP3A7 protein, humanCytochrome P-450 CYP3AImmunosuppressive AgentsTacrolimus

Identifiers

PMID30584253
PMCPMC6305386
OpenAlexW2906028817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.