Evidence map›Paper›PMID 30583681›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2018

Rate and Predictive Factors for Sustained Complete Response after Selective Transarterial Chemoembolization (TACE) in Patients with Hepatocellular Carcinoma

Kittipitch Bannangkoon, Keerati Hongsakul, Teeravut Tubtawee, Edward McNeil, Hutcha Sriplung, Virasakdi Chongsuvivatwong

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Article in Asian Pacific journal of cancer prevention : APJCP, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

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18citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Kittipitch BannangkoonDepartment of Radiology, Faculty of Medicine, Prince of Songkla University, 15 Kanchanavanit Road, Hat Yai, Songkhla, Thailand. Email: drkittipitch@gmail.com
Keerati Hongsakul
Teeravut Tubtawee
Edward McNeil
Hutcha Sriplung
Virasakdi Chongsuvivatwong

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To determine the effectiveness and performance of selective conventional transarterial chemoembolization (TACE) and analyze the potential predictive factors of sustained complete response (CR) for patients with hepatocellular carcinoma (HCC). Materials and Methods: Total of 52 patients with HCC (33 males, 19 females; mean age 64.0 ± 9.6 years) who underwent 81 sessions of selective TACE between November 2015 and March 2017 at Songklanagarind hospital were reviewed. The Kaplan-Meier method was used to describe CR rates at various time points. Univariate and multivariate logistic regression models were performed to determine the predictive factors for sustained CR at six months. Results: The CR rates after selective TACE at 1, 4, 6, 9 and 12 months were 87%, 81%, 62%, 40% and 31%, respectively. Univariate and multivariate analyses demonstrated that alpha fetoprotein level <100ng/ml, a tumor size in summation ≤ 30 mm, ≤ 2 sessions of selective TACE and unilobar involvement had a significantly higher odds of sustaining complete response at six months (p =0.018, 0.031, 0.032, and 0.044, respectively). Conclusions: Selective TACE has a good therapeutic results and can sustained complete response in selected HCC patients. Serum AFP≤ 100 ng/ml, a few sessions of selective TACE, tumor size in summation ≤ 30 mm and unilobar involvement were favorable predictive factors for sustained complete response of HCC patients.

Indexed as

AdultAgedAged, 80 and overalpha-FetoproteinsCarcinoma, HepatocellularChemoembolization, TherapeuticFemaleHumansLiver NeoplasmsMaleMiddle Agedalpha-FetoproteinsComplete responseHepatocellular carcinomapredictive factorsselective TACE

Identifiers

PMID30583681
PMCPMC6428524

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.