Trial reportInternational journal of environmental research and public health2018
Prenatal Household Air Pollution Alters Cord Blood Mononuclear Cell Mitochondrial DNA Copy Number: Sex-Specific Associations.
Trial report in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prenatal air pollution exposure in relation to the telomere-mitochondrial axis of aging at birth: A systematic review.Environmental research · 2024Pooled it
- Household air pollution exposures over pregnancy and maternal blood pressure trajectories through 8 years postpartum: Evidence from the Ghana Randomized Air Pollution and Health Study (GRAPHS).Environmental research · 2026Trial
- Prenatal Household Air Pollution Exposure and Childhood Blood Pressure in Rural Ghana.Environmental health perspectives · 2024Trial
- Effects of a LPG stove and fuel intervention on adverse maternal outcomes: A multi-country randomized controlled trial conducted by the Household Air Pollution Intervention Network (HAPIN).Environment international · 2023Trial
- A secondary data analysis of a cluster randomized controlled trial: improved cookstoves associated with reduction in incidence of low birthweight in rural Malawi.International journal of epidemiology · 2022Trial
- Trial
- Prenatal and postnatal household air pollution and longitudinal growth trajectories: results from long-term follow up of the GRAPHS cohort.Environment international · 2026Article
- Exploring Effects of Household Air Pollution on Pregnant Mothers and Their Offspring in Africa: A Scoping Review.International journal of environmental research and public health · 2026Article
- Prenatal humid heat exposure and cord blood extracellular vesicle microRNA profiles in a Ghanaian Pregnancy Cohort: GRAPHS.Environmental epigenetics · 2026Article
- Identifying sensitive windows of prenatal household air pollution on birth weight and infant pneumonia risk to inform future interventions.Environment international · 2023Article
- The prenatal environment and its influence on maternal and child mitochondrial DNA copy number and methylation: A review of the literature.Environmental research · 2023Review
- Mitochondrial DNA copy number dynamics and associations with the prenatal environment from birth through adolescence in a population of Dominican and African American children.Mitochondrion · 2023Article
- Did COVID-19 Change the Availability and Use of Clean Energy for Cooking? Evidence From Ghana.Environmental health insights · 2023Article
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- Article
- Article
- Trends in Research of Prenatal Stress From 2011 to 2021: A Bibliometric Study.Frontiers in pediatrics · 2022Article
- Mitochondrial DNA Copy Number Adaptation as a Biological Response Derived from an Earthquake at Intrauterine Stage.International journal of environmental research and public health · 2021Article
- Prenatal and Postnatal Household Air Pollution Exposure and Infant Growth Trajectories: Evidence from a Rural Ghanaian Pregnancy Cohort.Environmental health perspectives · 2021Article
- Cerebral cortex and blood transcriptome changes in mouse neonates prenatally exposed to air pollution particulate matter.Journal of neurodevelopmental disorders · 2021Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
backgroundAssociations between prenatal household air pollution (HAP) exposure or cookstove intervention to reduce HAP and cord blood mononuclear cell (CBMC) mitochondrial deoxyribonucleic acid copy number (mtDNAcn), an oxidative stress biomarker, are unknown. MATERIALS AND
methodsPregnant women were recruited and randomized to one of two cookstove interventions, including a clean-burning liquefied petroleum gas (LPG) stove, or control. Prenatal HAP exposure was determined by serial, personal carbon monoxide (CO) measurements. CBMC mtDNAcn was measured by quantitative polymerase chain reaction. Multivariable linear regression determined associations between prenatal CO and cookstove arm on mtDNAcn. Associations between mtDNAcn and birth outcomes and effect modification by infant sex were explored.
resultsLPG users had the lowest CO exposures (
conclusionsIncreased prenatal HAP exposure reduces CBMC mtDNAcn, suggesting cumulative prenatal oxidative stress injury. An LPG stove intervention may reverse this effect. Boys appear most susceptible.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.