Evidence map›Paper›PMID 30583538›Full record

ReviewCells2018

Impact of Autophagy of Innate Immune Cells on Inflammatory Bowel Disease.

Tomoya Iida, Yoshihiro Yokoyama, Kohei Wagatsuma, Daisuke Hirayama, Hiroshi Nakase

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 57 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Selected Cytokines and Metalloproteinases in Inflammatory Bowel Disease.International journal of molecular sciences · 2023
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Circular RNA TRAPPC6B inhibits intracellularClinical & translational immunology · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Interaction between HuR andMolecular and cellular biology · 2020
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tomoya IidaDepartment of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan. tomoya.iida.0306@gmail.com.ORCID 0000-0003-2842-8052
Yoshihiro YokoyamaDepartment of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan. yoshi_yokoyamaa@yahoo.co.jp.
Kohei WagatsumaDepartment of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan. waga_a05m@yahoo.co.jp.
Daisuke HirayamaDepartment of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan. hirarin95@yahoo.co.jp.ORCID 0000-0002-9842-4850
Hiroshi NakaseDepartment of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan. hiropynakase@gmail.com.ORCID 0000-0003-2848-6586
Sapporo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy, an intracellular degradation mechanism, has many immunological functions and is a constitutive process necessary for maintaining cellular homeostasis and organ structure. One of the functions of autophagy is to control the innate immune response. Many studies conducted in recent years have revealed the contribution of autophagy to the innate immune response, and relationships between this process and various diseases have been reported. Inflammatory bowel disease is an intractable disorder with unknown etiology; however, immunological abnormalities in the intestines are known to be involved in the pathology of inflammatory bowel disease, as is dysfunction of autophagy. In Crohn's disease, many associations with autophagy-related genes, such as

Indexed as

AutophagyAutophagy-Related ProteinsCrohn DiseaseAnimalsCytokinesDisease Models, AnimalGenetic Predisposition to DiseaseGTP-Binding ProteinsHumansImmunity, InnateInflammasomesMiceNod2 Signaling Adaptor ProteinPaneth CellsATG16L1 protein, humanAutophagy-Related ProteinsCytokinesGTP-Binding ProteinsInflammasomesIRGM protein, humanNOD2 protein, humanNod2 Signaling Adaptor ProteinautophagyCrohn’s diseaseimmune cellinflammasomeinflammatory bowel diseaseinnate immunityPaneth cell

Identifiers

PMID30583538
PMCPMC6356773
OpenAlexW2906245669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.