ArticleNanomaterials (Basel, Switzerland)2018
Impact of Quantum Dot Surface on Complex Formation with Chlorin e₆ and Photodynamic Therapy.
Article in Nanomaterials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 citing papers in PubMed, 23 citations in OpenAlex.
- Unveiling Theranostics: Nanocomplex-Assisted Photodynamic Eradication of Aggressive Cancer Cells and Modulation of Tumor-Associated Macrophages.International journal of nanomedicine · 2025Article
- Review
- Advances in Photodynamic Therapy Based on Nanotechnology and Its Application in Skin Cancer.Frontiers in oncology · 2022Review
- Hybrid Complexes of Photosensitizers with Luminescent Nanoparticles: Design of the Structure.Acta naturaeArticle
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Authors and funding
5 authors at 3 institutions in 1 country.
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Abstract
Nanomaterials have permeated various fields of scientific research, including that of biomedicine, as alternatives for disease diagnosis and therapy. Among different structures, quantum dots (QDs) have distinctive physico-chemical properties sought after in cancer research and eradication. Within the context of cancer therapy, QDs serve the role of transporters and energy donors to photodynamic therapy (PDT) drugs, extending the applicability and efficiency of classic PDT. In contrast to conventional PDT agents, QDs' surface can be designed to promote cellular targeting and internalization, while their spectral properties enable better light harvesting and deep-tissue use. Here, we investigate the possibility of complex formation between different amphiphilic coating bearing QDs and photosensitizer chlorin e₆ (Ce₆). We show that complex formation dynamics are dependent on the type of coating-phospholipids or amphiphilic polymers-as well as on the surface charge of QDs. Förster's resonant energy transfer occurred in every complex studied, confirming the possibility of indirect Ce₆ excitation. Nonetheless,
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