Evidence map›Paper›PMID 30583464›Full record

ArticleMolecules (Basel, Switzerland)2018

Binding of Small Molecules to G-quadruplex DNA in Cells Revealed by Fluorescence Lifetime Imaging Microscopy of

Ting-Yuan Tseng, I-Te Chu, Shang-Jyun Lin, Jie Li, Ta-Chau Chang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ting-Yuan TsengInstitute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, Taiwan. homeotic@gmail.com.
I-Te ChuInstitute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, Taiwan. r04223204@gmail.com.
Shang-Jyun LinInstitute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, Taiwan. john830110@gmail.com.
Jie LiInstitute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, Taiwan. julielee0531@gmail.com.
Ta-Chau ChangInstitute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, Taiwan. tcchang@po.iams.sinica.edu.tw.ORCID 0000-0001-5878-8556
Institute of Atomic and Molecular Sciences, Academia Sinica · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

G-quadruplex (G4) structures have recently received increasing attention as a potential target for cancer research. We used time-gated fluorescence lifetime imaging microscopy (FLIM) with a G4 fluorescent probe, 3,6-bis(1-methyl-2-vinylpyridinium) carbazole diiodide (

Indexed as

G-QuadruplexesMicroscopy, FluorescenceCarbazolesCircular DichroismDNAFluorescent DyesHumansLigandsPyridinium Compounds3,6-bis(1-methyl-4-vinylpyridium)carbazole diiodideCarbazolesDNAFluorescent DyesLigandsPyridinium Compoundsfluorescence lifetime imaging microscopyG4 ligandsG-quadruplexo-BMVC foci

Identifiers

PMID30583464
PMCPMC6337594
OpenAlexW2906240437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.