Evidence map›Paper›PMID 30583150›Full record

ArticleBiomaterials2019

A combined hiPSC-derived endothelial cell and in vitro microfluidic platform for assessing biomaterial-based angiogenesis.

Sylvia L Natividad-Diaz, Shane Browne, Amit K Jha, Zhen Ma, Samir Hossainy, Yosuke K Kurokawa, Steven C George, Kevin E Healy

Abstract read
In one paragraph

Article in Biomaterials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. RBM20 variants disrupt CaSignal transduction and targeted therapy · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Molecular therapy. Nucleic acids · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Biomaterial-basedCancer pathogenesis and therapy · 2023
    Review
  17. Review
  18. Review
  19. Article
  20. Engineering approaches for cardiac organoid formation and their characterization.Translational research : the journal of laboratory and clinical medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sylvia L Natividad-DiazDepartment of Bioengineering, University of California-Berkeley, Berkeley, CA, United States.
Shane BrowneDepartment of Bioengineering, University of California-Berkeley, Berkeley, CA, United States.
Amit K JhaDepartment of Bioengineering, University of California-Berkeley, Berkeley, CA, United States; Department of Materials Science and Engineering, University of California-Berkeley, Berkeley, CA, United States.
Zhen MaDepartment of Bioengineering, University of California-Berkeley, Berkeley, CA, United States.
Samir HossainyDepartment of Bioengineering, University of California-Berkeley, Berkeley, CA, United States; Department of Materials Science and Engineering, University of California-Berkeley, Berkeley, CA, United States.
Yosuke K KurokawaDepartment of Biomedical Engineering, Washington University in St Louis, MO, United States.
Steven C GeorgeDepartment of Biomedical Engineering, University of California-Davis, Davis, CA, United States.
Kevin E HealyDepartment of Bioengineering, University of California-Berkeley, Berkeley, CA, United States; Department of Materials Science and Engineering, University of California-Berkeley, Berkeley, CA, United States. Electronic address: kehealy@berkeley.edu.

Funding

Modeling metabolic interactions of liver and fat with integrated microphysiological systemsUH3TR000487 · NCATS · UNIVERSITY OF CALIFORNIA BERKELEY · PI HEALY, KEVIN EDWARD · 2014 to 2016
$2.9M
Disease-Specific Integrated Microphysiological Human Tissue ModelsUH2TR000487 · NCATS · UNIVERSITY OF CALIFORNIA BERKELEY · PI HEALY, KEVIN EDWARD, LEE, LUKE P. · 2012 to 2013
$1.8M
Stem Cell Engineering Training ProgramT32GM098218 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI HEALY, KEVIN EDWARD, SCHAFFER, DAVID V · 2011 to 2020
$1.8M
NCATS NIH HHS UH2 TR000487NCATS NIH HHS UH3 TR000487NIGMS NIH HHS T32 GM098218
6 · The paper itself

Abstract

Human induced pluripotent stem cell (hiPSC) derived angiogenesis models present a unique opportunity for patient-specific platforms to study the complex process of angiogenesis and the endothelial cell response to biomaterial and biophysical changes in a defined microenvironment. We present a refined method for differentiating hiPSCs into a CD31

Indexed as

Neovascularization, PhysiologicBiocompatible MaterialsCell DifferentiationCell LineEndothelial CellsEquipment DesignHumansHydrogelsInduced Pluripotent Stem CellsMicrofluidic Analytical TechniquesNeovascularization, PathologicBiocompatible MaterialsHydrogelsDifferentiationhiPSC-derived endothelial cells (hiPSC-ECs)Human induced pluripotent stem cells (hiPSCs)Hyaluronic acidHydrogelIn vitro angiogenesis model

Identifiers

PMID30583150
PMCPMC6453535

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.