ArticleJournal of cardiac failure2019
The Prevalence of Cognitive Impairment Among Adults With Incident Heart Failure: The "Reasons for Geographic and Racial Differences in Stroke" (REGARDS) Study.
Article in Journal of cardiac failure, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The trial behind it
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Who cites it
27 citing papers in PubMed, 34 citations in OpenAlex.
- Apixaban Versus Aspirin to Reduce Cognitive Decline After Cryptogenic Stroke and Atrial Cardiopathy: ARCADIA-Cognition Study.Journal of the American Heart Association · 2025Trial
- Heart Meets Brain: Insights into Neurocardiac Pathophysiology.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026Review
- Prevalence and Latent Profiles of Cognitive Impairment in Patients with Heart Failure: A Secondary Data Analysis.Journal of clinical medicine · 2026Article
- Hypoxia and Cognitive Functions in Patients Suffering from Cardiac Diseases: A Narrative Review.Journal of clinical medicine · 2025Review
- Association of Alzheimer's Disease and Related Dementias (ADRD) With Days at Home Among Medicare Beneficiaries After a Heart Failure Hospitalization.Circulation. Cardiovascular quality and outcomes · 2025Article
- Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment.ESC heart failure · 2025Review
- Trajectory of Cognitive Function After Incident Heart Failure.Circulation. Heart failure · 2025Article
- The Glymphatic System and Its Role in Neurovascular Diseases.Journal of neuroendovascular therapy · 2025Review
- Trajectory of Cardiogenic Dementia: A New Perspective.Journal of cellular and molecular medicine · 2025Review
- Factors Influencing the Development and Severity of Cognitive Decline in Patients with Chronic Heart Failure.Medicina (Kaunas, Lithuania) · 2024Article
- Trajectory of Cognitive Decline After Incident Heart Failure Hospitalization: Findings From the REGARDS Study.Journal of the American Heart Association · 2024Article
- Trajectory of Cognitive Function After Incident Heart Failure.medRxiv : the preprint server for health sciences · 2024Article
- Establishment, Prediction, and Validation of a Nomogram for Cognitive Impairment in Elderly Patients With Diabetes.Journal of diabetes research · 2024Article
- Cognitive impairment in patients with heart failure: molecular mechanism and therapy.Heart failure reviews · 2023Review
- Depressive symptoms, cognitive impairment, and all-cause mortality among REGARDS participants with heart failure.European heart journal open · 2022Article
- Cognitive Impairment in Heart Failure-A Review.Biology · 2022Review
- Social Determinants of Health and 30-Day Readmissions Among Adults Hospitalized for Heart Failure in the REGARDS Study.Circulation. Heart failure · 2022Article
- Cognitive Impairment in Acute Heart Failure: Narrative Review.Journal of cardiovascular development and disease · 2021Review
- Heart failure is independently associated with white matter lesions: insights from the population-based LIFE-Adult Study.ESC heart failure · 2021Article
- Cognitive impairment in patients hospitalized for congestive heart failure: data from the RICA Registry.Internal and emergency medicine · 2021Article
Corrections and comments
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Authors and funding
13 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundCognitive impairment (CI) is estimated to be present in 25%-80% of heart failure (HF) patients, but its prevalence at diagnosis is unclear. To improve our understanding of cognition in HF, we determined the prevalence of CI among adults with incident HF in the REGARDS study. METHODS AND
resultsREGARDS is a longitudinal cohort study of adults ≥45 years of age recruited in the years 2003-2007. Incident HF was expert adjudicated. Cognitive function was assessed with the Six-Item Screener. The prevalence of CI among those with incident HF was compared with the prevalence of CI among an age-, sex-, and race-matched cohort without HF. The 436 participants with incident HF had a mean age of 70.3 years (SD 8.9), 47% were female, and 39% were black. Old age, black race, female sex, less education, and anticoagulation use were associated with CI. The prevalence of CI among participants with incident HF (14.9% [95% CI 11.7%-18.6%]) was similar to the non-HF matched cohort (13.4% [11.6%-15.4%]; P < .43).
conclusionsA total of 14.9% of the adults with incident HF had CI, suggesting that the majority of cognitive decline occurs after HF diagnosis. Increased awareness of CI among newly diagnosed patients and ways to mitigate it in the context of HF management are warranted.
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