Evidence map›Paper›PMID 30582886›Full record

ArticleMolecular microbiology2019

The Cu chaperone CopZ is required for Cu homeostasis in Rhodobacter capsulatus and influences cytochrome cbb

Marcel Utz, Andreea Andrei, Martin Milanov, Petru-Iulian Trasnea, Dorian Marckmann, Fevzi Daldal, Hans-Georg Koch

Open access · bronzeAbstract read
In one paragraph

Article in Molecular microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Unique underlying principles shaping copper homeostasis networks.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2022
    Review
  8. Article
  9. Article
  10. Maturation ofFrontiers in microbiology · 2021
    Article
  11. Article
  12. The CopA2-Type PFrontiers in microbiology · 2021
    Article
  13. Review
  14. Article
  15. TheProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Marcel UtzFaculty of Medicine, Institut für Biochemie und Molekularbiologie, ZBMZ, Albert-Ludwigs-Universität Freiburg, Stefan-Meier-Strasse 17, Freiburg, 79104, Germany.
Andreea AndreiFaculty of Medicine, Institut für Biochemie und Molekularbiologie, ZBMZ, Albert-Ludwigs-Universität Freiburg, Stefan-Meier-Strasse 17, Freiburg, 79104, Germany.
Martin MilanovFaculty of Medicine, Institut für Biochemie und Molekularbiologie, ZBMZ, Albert-Ludwigs-Universität Freiburg, Stefan-Meier-Strasse 17, Freiburg, 79104, Germany.
Petru-Iulian TrasneaFaculty of Medicine, Institut für Biochemie und Molekularbiologie, ZBMZ, Albert-Ludwigs-Universität Freiburg, Stefan-Meier-Strasse 17, Freiburg, 79104, Germany.
Dorian MarckmannFaculty of Medicine, Institut für Biochemie und Molekularbiologie, ZBMZ, Albert-Ludwigs-Universität Freiburg, Stefan-Meier-Strasse 17, Freiburg, 79104, Germany.
Fevzi DaldalDepartment of Biology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Hans-Georg KochFaculty of Medicine, Institut für Biochemie und Molekularbiologie, ZBMZ, Albert-Ludwigs-Universität Freiburg, Stefan-Meier-Strasse 17, Freiburg, 79104, Germany.ORCID 0000-0001-5913-0334
University of Freiburg · DEUniversity of Pennsylvania · US

Funding

Respiratory Complex III: Supercomplexes and ROS, from Bacteria to HumanR01GM038237 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI DALDAL, M. FEVZI · 1987 to 2018
$5.9M
Basic Energy Sciences DE-FG02-91ER20052Deutsche Forschungsgemeinschaft GRK2202 IRTG1478National Institute of Health NIH GM38237NIGMS NIH HHS R01 GM038237
6 · The paper itself

Abstract

Cu homeostasis depends on a tightly regulated network of proteins that transport or sequester Cu, preventing the accumulation of this toxic metal while sustaining Cu supply for cuproproteins. In Rhodobacter capsulatus, Cu-detoxification and Cu delivery for cytochrome c oxidase (cbb

Indexed as

Protein MultimerizationBacterial ProteinsCopperElectron Transport Complex IVHomeostasisMolecular ChaperonesProtein BindingRhodobacter capsulatusBacterial Proteinscbb3 oxidaseCopperElectron Transport Complex IVMolecular Chaperones

Identifiers

PMID30582886
PMCPMC6417943
OpenAlexW2905779227

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.