Evidence map›Paper›PMID 30582802›Full record

ArticleACS applied materials & interfaces2019

Polymer Amphiphiles for Photoregulated Anticancer Drug Delivery.

Valentina Brega, Federica Scaletti, Xianzhi Zhang, Li-Sheng Wang, Prudence Li, Qiaobing Xu, Vincent M Rotello, Samuel W Thomas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Valentina BregaDepartment of Chemistry , Tufts University , 62 Talbot Avenue , Medford , Massachusetts 02155 , United States.
Federica ScalettiDepartment of Chemistry , University of Massachusetts Amherst , 710 North Pleasant Street , Amherst , Massachusetts 01003 , United States.
Xianzhi ZhangDepartment of Chemistry , University of Massachusetts Amherst , 710 North Pleasant Street , Amherst , Massachusetts 01003 , United States.
Li-Sheng WangDepartment of Chemistry , University of Massachusetts Amherst , 710 North Pleasant Street , Amherst , Massachusetts 01003 , United States.
Prudence LiDepartment of Biomedical Engineering , Tufts University , 4 Colby Street , Medford , Massachusetts 02155 , United States.
Qiaobing XuDepartment of Biomedical Engineering , Tufts University , 4 Colby Street , Medford , Massachusetts 02155 , United States.ORCID http://orcid.org/0000-0001-7323-7795
Vincent M RotelloDepartment of Chemistry , University of Massachusetts Amherst , 710 North Pleasant Street , Amherst , Massachusetts 01003 , United States.ORCID http://orcid.org/0000-0002-5184-5439
Samuel W ThomasDepartment of Chemistry , Tufts University , 62 Talbot Avenue , Medford , Massachusetts 02155 , United States.ORCID http://orcid.org/0000-0002-0811-9781

Funding

Singlet Oxygen Degradable Materials to Harness the Near-Infrared Biological Transparency Window EfficientlyR21EB022207 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI THOMAS, SAMUEL W · 2016 to 2017
$376k
NIBIB NIH HHS R21 EB022207
6 · The paper itself

Abstract

We report the synthesis of amphiphilic polymers featuring lipophilic stearyl chains and hydrophilic poly(ethylene glycol) polymers that are connected through singlet oxygen-cleavable alkoxyanthracene linkers. These amphiphilic polymers assembled in water to form micelles with diameters of ∼20 nm. Reaction of the alkoxyanthracene linkers with light and O

Indexed as

Drug Delivery SystemsCell SurvivalDoxorubicinDrug CarriersHeLa CellsHep G2 CellsHumansHydrophobic and Hydrophilic InteractionsMicellesNeoplasmsPolymersDoxorubicinDrug CarriersMicellesPolymersamphiphilic polymersdoxorubicindrug deliverylight-responsive materialsself-assembly

Identifiers

PMID30582802
PMCPMC6623983

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.