Evidence map›Paper›PMID 30582064›Full record

ArticleIBRO reports2019

Layer-specific expression of extracellular matrix molecules in the mouse somatosensory and piriform cortices.

Hiroshi Ueno, Shunsuke Suemitsu, Shinji Murakami, Naoya Kitamura, Kenta Wani, Yosuke Matsumoto, Motoi Okamoto, Takeshi Ishihara

Open access · goldAbstract read
In one paragraph

Article in IBRO reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Hiroshi UenoDepartment of Medical Technology, Kawasaki University of Medical Welfare, 288, Matsushima, Kurashiki, Okayama, 701-0193, Japan.
Shunsuke SuemitsuDepartment of Psychiatry, Kawasaki Medical School, Kurashiki, 701-0192, Japan.
Shinji MurakamiDepartment of Psychiatry, Kawasaki Medical School, Kurashiki, 701-0192, Japan.
Naoya KitamuraDepartment of Psychiatry, Kawasaki Medical School, Kurashiki, 701-0192, Japan.
Kenta WaniDepartment of Psychiatry, Kawasaki Medical School, Kurashiki, 701-0192, Japan.
Yosuke MatsumotoDepartment of Neuropsychiatry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, 700-8558, Japan.
Motoi OkamotoDepartment of Medical Technology, Graduate School of Health Sciences, Okayama University, Okayama, 700-8558, Japan.
Takeshi IshiharaDepartment of Psychiatry, Kawasaki Medical School, Kurashiki, 701-0192, Japan.
Kawasaki Medical School · JPOkayama University · JPKawasaki University of Medical Welfare · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the developing central nervous system (CNS), extracellular matrix (ECM) molecules have regulating roles such as in brain development, neural-circuit maturation, and synaptic-function control. However, excluding the perineuronal net (PNN) area, the distribution, constituent elements, and expression level of granular ECM molecules (diffuse ECM) present in the mature CNS remain unclear. Diffuse ECM molecules in the CNS share the components of PNNs and are likely functional. As cortical functions are greatly region-dependent, we hypothesized that ECM molecules would differ in distribution, expression level, and components in a region- and layer-dependent manner. We examined the layer-specific expression of several chondroitin sulfate proteoglycans (aggrecan, neurocan, and brevican), tenascin-R,

Indexed as

a.u., arbitrary unitsChABC, chondroitinase ABCCNS, central nervous systemCSPG, chondroitin sulfate proteoglycansECM, extracellular cellular matrixExtracellular matrixHABP, hyaluronic acid binding proteinHA, hyaluronic acidHapln1, hyaluronan and proteoglycan link protein 1Perineuronal netsPiriform cortexPNN, perineuronal ntesProteoglycansSomatosensory cortexWFA, Wisteria floribunda agglutininWisteria floribunda

Identifiers

PMID30582064
PMCPMC6293036
OpenAlexW2903521243

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.