Evidence map›Paper›PMID 30581850›Full record

ArticleBioMed research international2018

Composition Analysis and Feature Selection of the Oral Microbiota Associated with Periodontal Disease.

Wen-Pei Chen, Shih-Hao Chang, Chuan-Yi Tang, Ming-Li Liou, Suh-Jen Jane Tsai, Yaw-Ling Lin

Abstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Characterizing the supragingival microbiome of healthy pregnant women.Frontiers in cellular and infection microbiology · 2022
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  2. Topic Application of the ProbioticFrontiers in cellular and infection microbiology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wen-Pei ChenDepartment of Applied Chemistry, Providence University, Taichung City, Taiwan.
Shih-Hao ChangDepartment of Periodontics, Linkou Medical Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Chuan-Yi TangDepartment of Computer Science and Information Engineering, Providence University, Taichung City, Taiwan.ORCID 0000-0003-0729-1624
Ming-Li LiouDepartment of Medical Laboratory Science and Biotechnology, Yuanpei University of Medical Technology, Hsin-Chu City, Taiwan.
Suh-Jen Jane TsaiDepartment of Applied Chemistry, Providence University, Taichung City, Taiwan.
Yaw-Ling LinDepartment of Applied Chemistry, Providence University, Taichung City, Taiwan.ORCID 0000-0001-8151-684X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontitis is an inflammatory disease involving complex interactions between oral microorganisms and the host immune response. Understanding the structure of the microbiota community associated with periodontitis is essential for improving classifications and diagnoses of various types of periodontal diseases and will facilitate clinical decision-making. In this study, we used a 16S rRNA metagenomics approach to investigate and compare the compositions of the microbiota communities from 76 subgingival plagues samples, including 26 from healthy individuals and 50 from patients with periodontitis. Furthermore, we propose a novel feature selection algorithm for selecting features with more information from many variables with a combination of these features and machine learning methods were used to construct prediction models for predicting the health status of patients with periodontal disease. We identified a total of 12 phyla, 124 genera, and 355 species and observed differences between health- and periodontitis-associated bacterial communities at all phylogenetic levels. We discovered that the genera

Indexed as

BacteriaChronic PeriodontitisGingivaHumansMicrobiotaPhylogenyRNA, Ribosomal, 16SToothRNA, Ribosomal, 16S

Identifiers

PMID30581850
PMCPMC6276491

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.