ReviewAnnals of translational medicine2018
Subglottic secretion drainage for ventilator-associated pneumonia prevention: an underused efficient measure.
Review in Annals of translational medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The efficacy of subglottic secretion drainage in preventing ventilator-associated pneumonia in the intensive care unit: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Subglottic secretion drainage for preventing ventilator-associated pneumonia: an overview of systematic reviews and an updated meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2020Pooled it
- Personalized automatic management of tracheal cuff pressure and subglottic secretions drainage to prevent pneumonia in critically ill intubated patients. The MICROINHALO multicenter randomized controlled trial.Intensive care medicine · 2026Trial
- Safety and Efficacy of a Novel Automated Intelligent Suction Device (VapCare) Among Mechanically Ventilated Neurocritical Care Patients: A Prospective Randomized Trial.Neurocritical care · 2025Trial
- A Novel Supraglottic Suction Device in Mechanically Ventilated Patients: A Randomized Controlled Trial.Medical devices (Auckland, N.Z.) · 2025Trial
- Ventilator-Associated Pneumonia (VAP) Prevention Bundle: A Multicenter Cross-Sectional Saudi Study to Assess Knowledge, Adherence, and Perceived Barriers Among ICU Practitioners in Hail Region.Pathogens (Basel, Switzerland) · 2026Article
- Ceragenin-Coated Endotracheal Tubes for the Reduction of Ventilator-Associated Pneumonia: A Prospective, Longitudinal, Crossover, Interrupted Time, Implementation Study (CEASE VAP Study).Critical care explorations · 2026Article
- Application of active subglottic airway humidification in intermittent subglottic secretion drainage in patients with tracheostomy: a randomized controlled trial.Journal of anesthesia, analgesia and critical care · 2025Article
- Specialized nursing intervention on critically ill patient in the prevention of intubation-associated pneumonia: an integrative literature review.Acute and critical care · 2024Article
- Volume-based subglottic secretion drainage: a randomized controlled trial.Annals of medicine and surgery (2012) · 2024Article
- Article
- Optimal Concentration and Duration of Endotracheal Tube Coating to Achieve Optimal Antimicrobial Efficacy and Safety Balance: An In Vitro Study.Gels (Basel, Switzerland) · 2023Article
- Airway ultrasound to detect subglottic secretion above endotracheal tube cuff.The ultrasound journal · 2023Article
- How healthcare must respond to ventilator-associated pneumonia (VAP) in invasively mechanically ventilated COVID-19 patients.The American journal of emergency medicine · 2021Article
- Rapid-flow expulsion maneuver in subglottic secretion clearance to prevent ventilator-associated pneumonia: a randomized controlled study.Annals of intensive care · 2021Article
- Indicative Factors for 48 or More Hours of Mechanical Ventilation to Optimize the Use of Orotracheal Tubes with Supra-cuff Suction Devices: a Retrospective Study.SN comprehensive clinical medicine · 2021Article
- Chest physiotherapy: An important adjuvant in critically ill mechanically ventilated patients with COVID-19.Respiratory physiology & neurobiology · 2020Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Subglottic secretion drainage (SSD) is one of the recommended strategies to prevent ventilator-associated pneumonia (VAP) with a high level of evidence, especially regarding early-onset pneumonia. All meta-analysis found that the use of SSD reduces VAP occurrence with a relative risk (RR) reduction of 45%. In some of them, SSD reduces the duration of mechanical ventilation (MV) but without beneficial effect on intensive care unit (ICU) or hospital mortality. In spite of the edited recommendations, SSD has not been widely implemented in ICUs and remains underused. Several factors could account for this: doubts on the innocuousness of using SSD, persisting reservations on the SSD effect on other outcomes than VAP, a high variability in the volume of secretions suctioned between patients and, for each individual patient, during the period of MV and the initial increased expense of the specific endotracheal tubes (ETs) allowing SSD which limits the availability of these devices.
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