Evidence map›Paper›PMID 30581825›Full record

ArticleAnnals of translational medicine2018

Impact of hyperoxemia on mortality in critically ill patients with ventilator-associated pneumonia.

Sophie Six, Anahita Rouzé, Olivier Pouly, Julien Poissy, Frédéric Wallet, Sébastien Preau, Saad Nseir

Abstract read
In one paragraph

Article in Annals of translational medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Dangers of hyperoxia.Critical care (London, England) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sophie SixCHU Lille, Centre de Réanimation, Lille, France.
Anahita RouzéCHU Lille, Centre de Réanimation, Lille, France.
Olivier PoulyCHU Lille, Centre de Réanimation, Lille, France.
Julien PoissyCHU Lille, Centre de Réanimation, Lille, France.
Frédéric WalletCHU Lille, Centre de Biologie-Pathologie, Lille, France.
Sébastien PreauCHU Lille, Centre de Réanimation, Lille, France.
Saad NseirCHU Lille, Centre de Réanimation, Lille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe objective of this study was to assess the impact of hyperoxemia on mortality in critically ill patients with ventilator-associated pneumonia (VAP).

methodsThis observational study was performed in a 50-bed mixed intensive care unit (ICU) during a 1-year period. Quantitative microbiological confirmation was required for VAP diagnosis. Hyperoxemia was defined as peripheral capillary oxygen saturation (SpO

resultsNinety-three patients with VAP were all included in this study. ICU-mortality rate was 32% (30 of 93 patients). The mean percentage of time spent with hyperoxemia in survivors and nonsurvivors at ICU admission, before, after or at the time of VAP diagnosis was not significantly different. Multivariate analysis identified age, and sequential organ dysfunction assessment at the day of VAP occurrence as independent risk factors for ICU mortality [odds ratio (OR) =1.04 (95% CI, 1.01-1.08) per year, P=0.019; 1.19 (95% CI, 1.06-1.34) per point, P=0.003; respectively]. The time spent with hyperoxemia before VAP occurrence was not significantly associated with mechanical ventilation free days, or ICU length of stay.

conclusionsHyperoxemia at ICU admission, or during ICU stay, had no significant impact on ICU mortality in critically ill patients with VAP.

Indexed as

critical illnessHyperoxemiamechanical ventilation (MV)mortalityventilator-associated pneumonia (VAP)

Identifiers

PMID30581825
PMCPMC6275410

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.