ReviewSchizophrenia research. Cognition2019
The role of childhood trauma in cognitive performance in schizophrenia and bipolar disorder - A systematic review.
Review in Schizophrenia research. Cognition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Cognitive impairment in people with schizophrenia: an umbrella review.European archives of psychiatry and clinical neuroscience · 2022Pooled it
- Childhood trauma and hippocampal-dependent memory across the psychosis spectrum: a systematic review and meta-analysis.Journal of psychiatry & neuroscience : JPNPooled it
- Childhood Trauma and Frontoparietal Network Connectivity During Working Memory Task Performance in Individuals With Schizophrenia and Healthy Participants.The European journal of neuroscience · 2026Article
- Evaluating psychosis-specific effects of trauma exposure in early-onset and adult-onset psychosis.Psychological medicine · 2026Article
- Key protective factors that mitigate the impact of childhood trauma on poor mental health in adulthood: a scoping review protocol.BMJ open · 2026Article
- Striatum volume and affective symptomatology are associated with sleep in schizophrenia.Journal of psychiatric research · 2026Article
- Exploring the relationships between Early Childhood Adversity, Social Cognition, and Aggression in a South African Study of People Living with Schizophrenia.Schizophrenia research. Cognition · 2025Review
- Nonlinear associations between reported childhood trauma and cognitive impairment in schizophrenia spectrum disorders.Schizophrenia research · 2025Article
- Depressive and Negative Symptoms in the Early and Established Stages of Schizophrenia: Integrating Structural Brain Alterations, Cognitive Performance, and Plasma Interleukin 6 Levels.Biological psychiatry global open science · 2025Article
- Impact of childhood trauma on cognitive function in patients with bipolar disorder.Frontiers in psychiatry · 2025Article
- A systematic review and meta-analysis of the traumatogenic phenotype hypothesis of psychosis.BJPsych open · 2024Review
- Association of early life stress and cognitive performance in patients with schizophrenia and healthy controls.Schizophrenia research. Cognition · 2023Article
- Prevalence and Correlates of Comorbid Posttraumatic Stress Disorder in Schizophrenia-Spectrum Disorder: A Systematic Review and Meta-Analysis.Psychiatry investigation · 2023Article
- Childhood trauma and real-world social experiences in psychosis.Schizophrenia research · 2023Article
- Environmental Risk Factors and Cognitive Outcomes in Psychosis: Pre-, Perinatal, and Early Life Adversity.Current topics in behavioral neurosciences · 2023Review
- Association of childhood trauma with cognitive domains in adult patients with mental disorders and in non-clinical populations: a systematic review.Frontiers in psychology · 2023Review
- Basic symptoms of schizophrenia are related to symptoms of traumatic stress: A pivotal role of sensitization. An observational study.Medicine · 2022Observational
- The shallow cognitive map hypothesis: A hippocampal framework for thought disorder in schizophrenia.Schizophrenia (Heidelberg, Germany) · 2022Review
- Childhood maltreatment increases the suicidal risk in Chinese schizophrenia patients.Frontiers in psychiatry · 2022Article
- The Impact of theBrain sciences · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Childhood trauma (CT) has repeatedly been associated with cognitive deficits in patients with psychosis but many inconsistencies have been reported so that the nature of the relationship remains unclear. The purpose of this review was to better characterize the contribution of CT to cognitive deficits by considering the type, severity and frequency of childhood traumatic events and their relationships with psychosis at all stages. Relevant studies were identified via electronic and manual literature searches and included original studies that investigated the relationship between CT and higher cognitive performance or social cognitive performance in patients with schizophrenia, bipolar disorder and psychosis at all stages of the illness stages (i.e. ultra-high risk, first episode or chronic phase). Overall, a majority of studies reported that patients who experienced CT displayed deficits in general cognitive ability compared to patients with psychosis without such a history. Associations between CT and other cognitive function were more mixed. When comparing patient groups, the association between CT and cognitive function was more inconsistent in patients with chronic schizophrenia than in healthy participants, ultra-high risk individuals, first-episode patients and patients with chronic bipolar disorder. In understanding the variability in the reported relationships between CT and cognition across study populations, we highlight the variety of questionnaires used and discuss the likelihood of there being differences in cognitive function based on specific stressors, severity and frequency. Finally, we consider future research steps that may shed light on psychobiological mechanisms underlying CT and cognitive performance in patients with psychosis.
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