Evidence map›Paper›PMID 30581600›Full record

ArticleTranslational neuroscience2018

Hypoglossal-facial 'side'-to-side Neurorrhaphy Combined with Electrical Myostimulation for Facial Palsy in Rats.

Binbin Wang, Shiwei Wang, Song Liu, Shaodong Zhang, Dezhi Li, Junhua Li, Xiongweiye Huang, Michael Schumacher, Hong Wan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Binbin WangBeijing Neurosurgical Institute, Capital Medical University, Beijing 100050, China.
Shiwei WangU 1195, INSERM, Université Paris-Sud and Université Paris-Saclay, 94276 Le Kremlin-Bicêtre, France.
Song LiuBeijing Neurosurgical Institute, Capital Medical University, Beijing 100050, China.
Shaodong ZhangBeijing Neurosurgical Institute, Capital Medical University, Beijing 100050, China.
Dezhi LiDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
Junhua LiBeijing Neurosurgical Institute, Capital Medical University, Beijing 100050, China.
Xiongweiye HuangBeijing Neurosurgical Institute, Capital Medical University, Beijing 100050, China.
Michael SchumacherU 1195, INSERM, Université Paris-Sud and Université Paris-Saclay, 94276 Le Kremlin-Bicêtre, France.
Hong WanBeijing Neurosurgical Institute, Capital Medical University, Beijing 100050, China.
Capital Medical University · CNInserm · FRBeijing Tian Tan Hospital · CNUniversité Paris-Sud · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction This study investigated the effect of combining hypoglossal-facial nerve "side"-to-side neurorrhaphy and electrical myostimulation in a rat model of facial palsy. Methods Rats with facial nerve crush injury were subjected to control condition, monotherapy of either neurorrhaphy or electrical myostimulation, or bitherapy of the two treatments. After 1, 3, and 6 months, rats were performed the facial symmetry evaluation, electrophysiological examination and the retrograde labeling of motor neurons. Results As early as 3 months after injury, face symmetry significantly improved in rats of the bitherapy group. At 3 or 6 months after injury, either the parameters of electrophysiological examination or the number of labeled motor neurons were significantly increased in the bitherapy group than in any other group. Discussion The combination of neurorrhaphy and electrical myostimulation effectively promoted the functional recovery after facial nerve crush injury.

Indexed as

Animal modelElectrical myostimulationFacial palsyMotor action potentialNeurorrhaphyRetrograde labeling

Identifiers

PMID30581600
PMCPMC6294042
OpenAlexW2905544797

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.