Evidence map›Paper›PMID 30581533›Full record

ArticleOxidative medicine and cellular longevity2018

Redox Profiling Reveals Clear Differences between Molecular Patterns of Wound Fluids from Acute and Chronic Wounds.

Edina Bodnár, Edina Bakondi, Katalin Kovács, Csaba Hegedűs, Petra Lakatos, Agnieszka Robaszkiewicz, Zsolt Regdon, László Virág, Éva Szabó

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  4. A synergistic multimodality treatment approach to address the key drivers of wound chronicity.Journal of vascular surgery. Venous and lymphatic disorders · 2026
    Review
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  13. Wound fluid sampling methods for proteomic studies: A scoping review.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2022
    Article
  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Edina BodnárDepartment of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Edina BakondiDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Katalin KovácsMTA-DE Cell Biology and Signaling Research Group, Debrecen, Hungary.
Csaba HegedűsDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Petra LakatosDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Agnieszka RobaszkiewiczDepartment of General Biophysics, University of Łódź, Łódź, Poland.
Zsolt RegdonDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
László VirágDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.ORCID 0000-0002-7099-6718
Éva SzabóDepartment of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.ORCID 0000-0002-9588-9281
University of Debrecen · HUUniversity of Łódź · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound healing is a complex multiphase process which can be hampered by many factors including impaired local circulation, hypoxia, infection, malnutrition, immunosuppression, and metabolic dysregulation in diabetes. Redox dysregulation is a common feature of many skin diseases demonstrated by virtually all cell types in the skin with overproduction of reactive oxygen and nitrogen species. The objective of this study was to characterize the redox environment in wound fluids and sera from patients suffering from chronic leg ulcers (

Indexed as

AgedAged, 80 and overFemaleGlutathioneHumansInterleukin-8Lipid PeroxidationL-Lactate DehydrogenaseMaleMiddle AgedOxidation-ReductionPoly Adenosine Diphosphate RibosePoly (ADP-Ribose) Polymerase-1Protein CarbonylationThiobarbituric Acid Reactive SubstancesTumor Necrosis Factor-alpha3-nitrotyrosineGlutathioneInterleukin-8L-Lactate DehydrogenasePARP1 protein, humanPoly Adenosine Diphosphate RibosePoly (ADP-Ribose) Polymerase-1Thiobarbituric Acid Reactive SubstancesTumor Necrosis Factor-alphaTyrosineVascular Endothelial Growth Factor A

Identifiers

PMID30581533
PMCPMC6276414
OpenAlexW2901960864

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.