Evidence map›Paper›PMID 30581461›Full record

ArticleDermatology research and practice2018

Investigation of Interleukin-27 in the Sera of Nonmelanoma Skin Cancer Patients.

Mehdi Ghahartars, Shiva Najafzadeh, Shabnam Abtahi, Mohammad Javad Fattahi, Abbas Ghaderi

Open access · goldAbstract read
In one paragraph

Article in Dermatology research and practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mehdi GhahartarsDepartment of Dermatology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Shiva NajafzadehShiraz Institute for Cancer Research, School of medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Shabnam AbtahiShiraz Institute for Cancer Research, School of medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Mohammad Javad FattahiShiraz Institute for Cancer Research, School of medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Abbas GhaderiShiraz Institute for Cancer Research, School of medicine, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0003-0849-3375
Shiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IL-27 has been shown to have both tumor promoting and suppressing functions. IL-27, with its diverse influences on immune responses, has not been studied extensively in nonmelanoma skin cancers (NMSC), including Squamous and Basal Cell Carcinomas (SCC and BCC), and its roles in tumor initiation, progression, and its probable use in NMSC treatment have yet to be unveiled. A cross-sectional analytical study was designed to investigate the serum levels of IL-27 in NMSC patients in comparison to normal individuals. Levels of IL-27 in the sera of 60 NMSC patients along with 28 healthy controls were measured by means of quantitative enzyme-linked immunosorbent assay (ELISA). In this study we observed that IL-27 serum levels were significantly higher in NMSC patients in comparison to healthy individuals (0.0134

Identifiers

PMID30581461
PMCPMC6276429
OpenAlexW2900729246

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.