Evidence map›Paper›PMID 30581386›Full record

ArticleFrontiers in pharmacology2018

Pimavanserin and Lorcaserin Attenuate Measures of Binge Eating in Male Sprague-Dawley Rats.

Amanda E Price, Victoria D Brehm, Jonathan D Hommel, Noelle C Anastasio, Kathryn A Cunningham

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. The Effect of Serotonin 5-HTAddiction biology · 2025
    Article
  3. 5-HTNutrients · 2023
    Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amanda E PriceCenter for Addiction Research, University of Texas Medical Branch, Galveston, TX, United States.
Victoria D BrehmCenter for Addiction Research, University of Texas Medical Branch, Galveston, TX, United States.
Jonathan D HommelCenter for Addiction Research, University of Texas Medical Branch, Galveston, TX, United States.
Noelle C AnastasioCenter for Addiction Research, University of Texas Medical Branch, Galveston, TX, United States.
Kathryn A CunninghamCenter for Addiction Research, University of Texas Medical Branch, Galveston, TX, United States.
The University of Texas Medical Branch at Galveston · US

Funding

Translational Addiction Sciences CenterP50DA033935 · NIDA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI MOELLER, FREDERICK GERARD · 2013 to 2017
$6.7M
Translational Explorations in Substance Use DisordersT32DA007287 · NIDA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI Kathryn A. Cunningham, Jonathan Dean Hommel · 1994 to 2026
$4.7M
Integration of Hypothalamic and Limbic Pathways to Regulate Motivation for FoodR01DK106229 · NIDDK · UNIVERSITY OF TEXAS MED BR GALVESTON · PI HOMMEL, JONATHAN DEAN · 2016 to 2020
$1.8M
Interrogation of Insular Excitatory/Inhibitory Balance in Cocaine-Associated Cue ReactivityF30DA042617 · NIDA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI PRICE, AMANDA ELIZABETH · 2016 to 2019
$139k
NIDA NIH HHS F30 DA042617NIDA NIH HHS P50 DA033935NIDA NIH HHS T32 DA007287NIDDK NIH HHS R01 DK106229
6 · The paper itself

Abstract

Binge eating disorder (BED) is characterized by dysregulated feeding and reward-related processes, and treatment is often challenged by limited therapeutic options. The serotonin (5-HT) 5-HT

Indexed as

5-HT2A receptor5-HT2C receptorbinge eatinglorcaserinpimavanserin

Identifiers

PMID30581386
PMCPMC6293203
OpenAlexW2902016260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.