Evidence map›Paper›PMID 30581370›Full record

ArticleMediators of inflammation2018

Activation of Macrophages by Oligomeric Proteins of Different Size and Origin.

Indrė Dalgėdienė, Asta Lučiūnaitė, Aurelija Žvirblienė

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Indrė DalgėdienėInstitute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius LT-10257, Lithuania.ORCID 0000-0003-4113-4761
Asta LučiūnaitėInstitute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius LT-10257, Lithuania.
Aurelija ŽvirblienėInstitute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius LT-10257, Lithuania.
Vilnius University · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activation of macrophages is one of the key processes in generating the immune response against pathogens or misfolded/aggregated otherwise unharmful host's proteins. Antigens and their immune complexes (IC) may shape macrophage phenotype in various directions. Data on the impact of protein structure during inflammation are evident; however, some separate steps of this process involving changes in macrophage phenotype are not fully understood. Our aim was to investigate the phenotype of macrophages after activation with different oligomeric proteins and their IC. We have used amyloid beta (A

Indexed as

Amyloid beta-PeptidesAnimalsCell LineCells, CulturedCytokinesMacrophage ActivationMacrophagesMiceTumor Necrosis Factor-alphaAmyloid beta-PeptidesCytokinesTumor Necrosis Factor-alpha

Identifiers

PMID30581370
PMCPMC6276464
OpenAlexW2901707950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.