ArticleJournal of medical biochemistry2018
Association Between Vitamin D Deficiencies in Sarcoidosis with Disease Activity, Course of Disease and Stages of Lung Involvements.
Article in Journal of medical biochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 29 citations in OpenAlex.
- Sarcoid Nodular Myopathy Presenting With Hypercalcemia: A Rare Presentation-Case Report.Clinical case reports · 2026Article
- The Impact of Nutritional Status on Survival and Development of Sarcoidosis: A Scoping Review of Current Evidence and Research Gaps.Nutrients · 2026Review
- Infectious and non-infectious precipitants of sarcoidosis.Journal of autoimmunity · 2024Review
- Article
- Calcium, Phosphate, and Vitamin D Status in Patients with Sarcoidosis-Associations with Disease Activity and Symptoms.Journal of clinical medicine · 2023Article
- Observational
- Vitamin D Status and Potential Therapeutic Options in Critically Ill Patients: A Narrative Review of the Clinical Evidence.Diagnostics (Basel, Switzerland) · 2022Review
- The Evolving Landscape of Cutaneous Sarcoidosis: Pathogenic Insight, Clinical Challenges, and New Frontiers in Therapy.American journal of clinical dermatology · 2022Review
- A validated FFQ to determine dietary intake of vitamin D.Public health nutrition · 2021Article
- Telomere length assessment in blood leukocytes of patients with sarcoidosis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2021Article
- Article
- Assessment of Abbott Architect 25-OH vitamin D assay in different levels of vitamin D.Journal of medical biochemistry · 2020Article
- Osseous manifestations of sarcoidosis.Reumatologia · 2020Review
- Correlation of Fgf23 and Balp with Bone Mineral Density in Hemodialysis Patients.Journal of medical biochemistry · 2019Article
- Soluble sPD-L1 and Serum Amyloid A1 as Potential Biomarkers for Lung Cancer.Journal of medical biochemistry · 2019Article
- Association of OverexpressedJournal of medical biochemistry · 2019Article
- Spirometry, cardiopulmonary exercise testing and the six-minute walk test results in sarcoidosis patients.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2019Article
- Evaluation of the Reliability and Validity of the Persian Version of the Fatigue Assessment Scale in Iranian Sarcoidosis Patients.Open access Macedonian journal of medical sciences · 2018Article
- Sarcoidosis and calcium homeostasis disturbances-Do we know where we stand?Chronic respiratory diseaseReview
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite negative association between 25-hydroxy vitamin D and incidence of many chronic respiratory diseases, this feature was not well studied in sarcoidosis. Current study investigated the association between 25-hydroxy vitamin D deficiency with sarcoidosis chronicity, disease activity, extra-pulmonary skin manifestations, urine calcium level and pulmonary function status in Iranian sarcoidosis patients. Results of this study along with future studies, will supply more effective programs for sarcoidosis treatment.
methodsEighty sarcoidosis patients in two groups of insufficient serum level and sufficient serum level of 25-hydroxy vitamin D were studied. Course of sarcoidosis was defined as acute and chronic sarcoidosis. Pulmonary function test (PFT) was assessed by spirometry. Skin involvements were defined as biopsy proven skin sarcoidosis. 24-hour urine calcium level was used to specify the disease activity. Stages of lung involvements were obtained by CT-scan and chest X-ray. The statistical analyses were evaluated using Statistical Package for the Social Sciences.
resultsA significant negative correlation was obtained between vitamin D deficiency in sarcoidosis patients and disease chronic course and stages two to four of lung involvements. Considering other parameters of the disease and vitamin D deficiency, no significant correlation was detected.
conclusionsIn conclusion, results of the current study implies in the role of vitamin 25(OH)D deficiencies in predicting the course of chronic sarcoidosis. Furthermore, it was concluded that vitamin 25(OH)D deficiency can direct pulmonary sarcoidosis toward stage 2-4 of lung involvements.
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